D
David W. Oldach
Researcher at University of Maryland, Baltimore
Publications - 62
Citations - 3448
David W. Oldach is an academic researcher from University of Maryland, Baltimore. The author has contributed to research in topics: Pfiesteria piscicida & Pfiesteria. The author has an hindex of 21, co-authored 60 publications receiving 3347 citations. Previous affiliations of David W. Oldach include North Carolina State University & University of Maryland, College Park.
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Journal ArticleDOI
Determinants of Viral Clearance and Persistence during Acute Hepatitis C Virus Infection
Robert Thimme,David W. Oldach,Kyong-Mi Chang,Kyong-Mi Chang,Carola Steiger,Stuart C. Ray,Francis V. Chisari +6 more
TL;DR: The virological and immunological features of hepatitis C virus (HCV) infection were studied weekly for 6 months after accidental needlestick exposure in five health care workers, four of whom developed acute hepatitis that progressed to chronicity while one subject cleared the virus.
Journal ArticleDOI
Differential CD4+ and CD8+ T-cell responsiveness in hepatitis C virus infection☆
Kyong-Mi Chang,Kyong-Mi Chang,Robert Thimme,Jacqueline J. Melpolder,David W. Oldach,Janell Pemberton,Jacquelyn Moorhead-Loudis,John G. McHutchison,Harvey J. Alter,Francis V. Chisari +9 more
TL;DR: The results show that a vigorous and multispecific CD4+ proliferative T‐cell response is maintained indefinitely after recovery from HCV infection whereas it is weak and focused in persistently infected patients.
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Development of Real-Time PCR Assays for Rapid Detection of Pfiesteria piscicida and Related Dinoflagellates
Holly A. Bowers,Torstein Tengs,Howard B. Glasgow,JoAnn M. Burkholder,Parke A. Rublee,David W. Oldach +5 more
TL;DR: A real-time PCR-based assay is developed that permits rapid and specific identification of Pfiesteria complex species in culture and heterogeneous environmental water samples and will be useful for many other applications, including adaptation for field-based technology.
Journal ArticleDOI
Retention of transcriptionally active cryptophyte nuclei by the ciliate Myrionecta rubra.
TL;DR: It is shown that Cryptophyte nuclei in M. rubra are retained for up to 30 days, are transcriptionally active and service plastids derived from multiple cryptophyte cells, and represents a previously unknown evolutionary strategy for acquiring biochemical potential.
Journal ArticleDOI
Learning and memory difficulties after environmental exposure to waterways containing toxin-producing Pfiesteria or Pfiesteria-like dinoflagellates
Lynn M. Grattan,David W. Oldach,Trish M. Perl,Trish M. Perl,Mark H. Lowitt,Diane L. Matuszak,Curtis Dickson,Colleen Parrott,Ritchie C Shoemaker,C. Lisa Kauffman,Martin P Wasserman,J. Richard Hebel,Patricia Charache,Patricia Charache,J. Glenn Morris +14 more
TL;DR: People with environmental exposure to waterways in which Pfiesteria toxins are present are at risk of developing a reversible clinical syndrome characterised by difficulties with learning and higher cognitive functions.