U
Uddalak Majumdar
Researcher at Nationwide Children's Hospital
Publications - 28
Citations - 404
Uddalak Majumdar is an academic researcher from Nationwide Children's Hospital. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 9, co-authored 22 publications receiving 266 citations. Previous affiliations of Uddalak Majumdar include University of Illinois at Chicago & University of Calcutta.
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Journal ArticleDOI
Epigenetic mechanisms underlying maternal diabetes-associated risk of congenital heart disease
Madhumita Basu,Jun-yi Zhu,Stephanie LaHaye,Stephanie LaHaye,Uddalak Majumdar,Kai Jiao,Zhe Han,Vidu Garg,Vidu Garg +8 more
TL;DR: A gene-environment interaction between maternal hyperglycemia and Notch signaling is identified and support a model in which environmental factors cause birth defects in genetically susceptible infants.
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Endothelial Notch1 Is Required for Proper Development of the Semilunar Valves and Cardiac Outflow Tract.
Sara N. Koenig,Kevin Bosse,Uddalak Majumdar,Elizabeth M. Bonachea,Freddy Radtke,Vidu Garg,Vidu Garg +6 more
TL;DR: The data demonstrate the role of endothelial Notch1 in the proper development of the semilunar valves and cardiac outflow tract and recapitulate the congenital cardiac phenotype of Notch 1 +/− ;Nos3 −/− embryos.
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In vivo protein tyrosine nitration in S. cerevisiae: identification of tyrosine-nitrated proteins in mitochondria.
Arindam Bhattacharjee,Uddalak Majumdar,Debasis Maity,Tuhin Subhra Sarkar,Achintya Mohan Goswami,Rupam Sahoo,Sanjay Ghosh +6 more
TL;DR: This investigation is the first comprehensive study to identify mitochondrial proteins nitrated in vivo and two target mitochondrial proteins are aconitase and isocitrate dehydrogenase that are involved directly in the citric acid cycle.
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Regulation of Golgi Cisternal Progression by Ypt/Rab GTPases
TL;DR: This work establishes the localization of Ypt1 and Ypt31 to opposite faces of the Golgi: early and late, respectively, and shows that Ypt/Rab GTPases regulate two separate steps of Golgi cisternal progression.
Journal ArticleDOI
Nitric oxide prevents aortic valve calcification by S-nitrosylation of USP9X to activate NOTCH signaling
Uddalak Majumdar,Sathiyanarayanan Manivannan,Madhumita Basu,Madhumita Basu,Y. Ueyama,Mark C. Blaser,Emily Cameron,Michael R. McDermott,Joy Lincoln,Susan E. Cole,Stephen A. Wood,Elena Aikawa,Brenda Lilly,Brenda Lilly,Vidu Garg +14 more
TL;DR: In this article, an unbiased proteomic approach to identify S-nitrosylated proteins in valve cells found enrichment of the ubiquitin-proteasome pathway and implicated USP9X (ubiquitin specific peptidase 9, X-linked) in NOTCH regulation during calcification.