Urs Albrecht

TL;DR: The orphan nuclear receptor REV-ERBalpha is identified as the major regulator of cyclic Bmal1 transcription, and constitutes a molecular link through which components of the negative limb drive antiphasic expression of component of the positive limb.

TL;DR: This work discusses knowledge acquired during the past few years on the complex structure and function of the mammalian circadian timing system and some of the SCN output pathways serve as input pathways for peripheral tissues.

TL;DR: Developmental arrest in Brca2-deficient embryos, their radiation sensitivity, and the association of Brca1 with Rad51 indicate that Brca 2 may be an essential cofactor in the Rad51-dependent DNA repair of double-strand breaks, thereby explaining the tumour-suppressor function of BrCA2.

TL;DR: It is shown that Wnt3 is expressed before gastrulation in the proximal epiblast of the egg cylinder, then is restricted to the posterior proximalEpiblast and its associated visceral endoderm and subsequently to the primitive streak and mesoderm, and the subsequent establishment of anterior-posterior neural pattern in the ectoderm is dependent on derivatives of the primitive streaks.

TL;DR: It appears that mper1 is the pacemaker component which responds to light and thus mediates photic entrainment in Drosophila period and mper2.