V
V. Prévot
Publications - 42
Citations - 132
V. Prévot is an academic researcher. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 7, co-authored 42 publications receiving 132 citations.
Papers
More filters
Journal ArticleDOI
GnRH replacement rescues cognition in Down syndrome
Maria Manfredi-Lozano,Valerie Leysen,Michela Adamo,Isabel Paiva,Renaud Rovera,Jean-Michel Pignat,Fatima Ezzahra Timzoura,Michael Candlish,Sabiha Eddarkaoui,Samuel A. Malone,Mauro S.B. Silva,Sara Trova,Monica Imbernon,Laurine Decoster,L. Cotellessa,Manuel Tena-Sempere,Marc Claret,Ariane Paoloni-Giacobino,Damien Plassard,Emmanuelle Paccou,Nathalie Vionnet,James Jr Acierno,Aleksandra Maleska Maceski,Antoine Lutti,Frank W. Pfrieger,Sowmyalakshmi Rasika,Federico Santoni,Ulrich Boehm,Philippe Ciofi,Luc Buée,Nasser Haddjeri,Anne-Laurence Boutillier,Jens Kuhle,A. Messina,Bogdan Draganski,Paolo Giacobini,Nelly Pitteloud,V. Prévot +37 more
TL;DR: Epigenetic, cellular, chemogenetic, and pharmacological interventions that restore physiological GnRH levels abolish olfactory and cognitive defects in Ts65Dn mice, whereas pulsatile GnRH therapy improves cognition and brain connectivity in adult DS patients.
Journal ArticleDOI
Tanycytes control hypothalamic liraglutide uptake and its anti-obesity actions.
Monica Imbernon,C. Saponaro,Hans Christian Cederberg Helms,Manon Duquenne,Daniela Fernandois,Eleonora Deligia,Raphael G. P. Denis,Daniela Herrera Moro Chao,Sowmyalakshmi Rasika,Bart Staels,François Pattou,Frank W. Pfrieger,Birger Brodin,Serge Luquet,Caroline Bonner,V. Prévot +15 more
TL;DR: In this paper , the authors demonstrate that liraglutide is shuttled to target cells in the mouse hypothalamus by specialized ependymoglial cells called tanycytes, bypassing the blood-brain barrier.
Journal ArticleDOI
Inhibition of carnitine palmitoyl-transferase 1A in hepatic stellate cells protects against fibrosis.
Marcos F. Fondevila,Uxia Fernandez,Violeta Heras,Tamara Parracho,Maria J. Gonzalez-Rellan,Eva Novoa,Begoña Porteiro,Cristina Alonso,Rebeca Mayo,Natália da Silva Lima,Cristina Iglesias,Aveline Filliol,Ana Senra,Teresa C. Delgado,Ashwin Woodhoo,Laura Herrero,Dolors Serra,V. Prévot,Markus Schwaninger,Miguel López,Carlos Dieguez,Oscar Millet,José M. Mato,Francisco Javier Cubero,Marta Varela-Rey,Paula Iruzubieta,Javier Crespo,María L. Martínez-Chantar,Robert F. Schwabe,Rubén Nogueiras +29 more
TL;DR: In this article , the role of fatty acid oxidation and carnitine palmitoyltransferase 1A (CPT1A) in the development of liver fibrosis was investigated.
Journal ArticleDOI
Melatonin drugs inhibit SARS-CoV-2 entry into the brain and virus-induced damage of cerebral small vessels
Erika Cecon,Daniela Fernandois,Nicolas Renault,Caio Coelho,Jan Wenzel,Corentin Bedart,Charlotte Izabelle,Sarah Gallet,Sophie Le Poder,Bernard Klonjkowski,Markus Schwaninger,V. Prévot,Julie Dam,Ralf Jockers +13 more
TL;DR: In this paper , the authors showed that melatonin and two melatonin-derived marketed drugs, agomelatine and ramelteon, prevent SARS-CoV-2 entry in the brain, thereby reducing virus-induced damage of small cerebral vessels, immune cell infiltration and brain inflammation.
Journal ArticleDOI
Prolonged breastfeeding protects from obesity by hypothalamic action of hepatic FGF21
Veronica Pena-Leon,Cintia Folgueira,Silvia Barja-Fernandez,Raquel Perez-Lois,Natália da Silva Lima,Marion Martin,Violeta Heras,Sara Martínez-Martínez,Paola Valero,Cristina Iglesias,Mannon Duquenne,Omar Al-Massadi,Daniel Beiroa,Yara Souto,Miguel Fidalgo,Rasika Sowmyalakshmi,Diana Guallar,Juan Cuñarro,Cecilia Castelao,Ana Senra,Patricia Gonzalez-Saenz,Rocío Vázquez-Cobela,Rosaura Leis,Guadalupe Sabio,Helge Mueller-Fielitz,Markus Schwaninger,Miguel López,Sulay Tovar,Felipe F. Casanueva,Emmanuel Valjent,Carlos Dieguez,V. Prévot,Rubén Nogueiras,Luisa M. Seoane +33 more
TL;DR: In this article , the effects of prolonged suckling are mediated by increased hepatic fibroblast growth factor 21 (FGF21) production and tanycyte-controlled access to the hypothalamus in adulthood.