V
Valentin Wittmann
Researcher at University of Konstanz
Publications - 129
Citations - 3199
Valentin Wittmann is an academic researcher from University of Konstanz. The author has contributed to research in topics: Glycosyl & Glycoprotein. The author has an hindex of 32, co-authored 125 publications receiving 2900 citations. Previous affiliations of Valentin Wittmann include Russian Academy of Sciences & Technische Universität München.
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Machine learning prediction of cyanobacterial toxin (microcystin) toxicodynamics in humans.
Stefan Altaner,Sabrina Jaeger,Regina Fotler,Ivan Zemskov,Valentin Wittmann,Falk Schreiber,Falk Schreiber,Daniel R. Dietrich +7 more
TL;DR: The inhibition of PPP1, PPP2A and PPP5 was determined with 18 structurally different MC and demonstrated MC congener dependent inhibition activity and a lower susceptibility of P PP5 to inhibition than PPP 1 and P PP2A.
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Cyclopropene derivatives of aminosugars for metabolic glycoengineering.
TL;DR: A comparative study of six cyclopropene-modified hexosamine derivatives and their suitability for MGE found that the amide-linked Cp-modified glucosamine derivative but not the Cyoc-modified glucose derivative is metabolically converted to the corresponding sialic acid.
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Simultaneous Detection of 14 Microcystin Congeners from Tissue Samples Using UPLC- ESI-MS/MS and Two Different Deuterated Synthetic Microcystins as Internal Standards
Stefan Altaner,Jonathan Puddick,Valérie Fessard,Daniel Feurstein,Ivan Zemskov,Valentin Wittmann,Daniel R. Dietrich +6 more
TL;DR: Two synthetic deuterated MC standards were applied and the tissue extraction protocol was optimised for the simultaneous detection of 14 MC congeners in a single ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) run, allowing for summary hazard and risk assessment.
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1H-Tetrazole as Catalyst in Phosphomorpholidate Coupling Reactions: Efficient Synthesis of GDP-Fucose, GDP-Mannose, and UDP-Galactose.
Valentin Wittmann,Chi-Huey Wong +1 more
TL;DR: In this paper, an improved procedure was described for the efficient and high-yield (76−91%) synthesis of nucleoside diphosphate sugars from the readily available 5'-monophosphomorpholidate and sugar 1-phosphate in the presence of 1H-tetrazole.