V
Veronica Escalante
Researcher at University of California, San Francisco
Publications - 6
Citations - 95
Veronica Escalante is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Metabolic network & Metabolomics. The author has an hindex of 2, co-authored 4 publications receiving 27 citations. Previous affiliations of Veronica Escalante include University of California, Berkeley.
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Journal ArticleDOI
Functional genetics of human gut commensal Bacteroides thetaiotaomicron reveals metabolic requirements for growth across environments
Hualan Liu,Anthony L. Shiver,Morgan N. Price,Hans K. Carlson,Valentine V. Trotter,Yan Chen,Veronica Escalante,Jayashree Ray,Kelsey E. Hern,Christopher J. Petzold,Peter J. Turnbaugh,Kerwyn Casey Huang,Adam P. Arkin,Adam P. Arkin,Adam M. Deutschbauer,Adam M. Deutschbauer +15 more
TL;DR: In this article, the authors measured the growth of a barcoded transposon mutant library of the gut commensal Bacteroides thetaiotaomicron on 48 carbon sources, in the presence of 56 stress-inducing compounds, and during mono-colonization of gnotobiotic mice.
Journal ArticleDOI
Bacterial alginate regulators and phage homologs repress CRISPR-Cas immunity.
Adair L. Borges,Bardo Castro,Sutharsan Govindarajan,Sutharsan Govindarajan,Tina Solvik,Veronica Escalante,Joseph Bondy-Denomy,Joseph Bondy-Denomy +7 more
TL;DR: The identification of the KinB–AlgB two-component system, known to modulate alginate biosynthesis, together with downstream proteins that repress the Type I-F CRISPR–Cas system in Pseudomonas aeruginosa, elucidates how bacteria control the expression of nucleolytic host defence systems to minimize the potential risks of self-targeting.
Journal ArticleDOI
A thermogenic fat-epithelium cell axis regulates intestinal disease tolerance
Kevin Man,Kevin Man,Christopher Bowman,Kristina N. Braverman,Veronica Escalante,Yuan Tian,Jordan E. Bisanz,Kirthana Ganeshan,Biao Wang,Andrew D. Patterson,James R. Bayrer,Peter J. Turnbaugh,Ajay Chawla +12 more
TL;DR: Evidence is provided that a thermogenic fat–epithelial cell axis regulates intestinal disease tolerance during experimental colitis, and it is found that the program of disease tolerance is preferentially expressed in thermoneutral mice, which protects them from injury-induced colitis and inflammation-induced colon cancer.
Posted ContentDOI
Systems biology illuminates alternative metabolic niches in the human gut microbiome
Cecilia Noecker,Juan-Maria Sanchez,Jordan E. Bisanz,Veronica Escalante,Margaret Alexander,Kai Trepka,Almut Heinken,Yuanyuan Liu,Dylan Dodd,Ines Thiele,Brian DeFelice,Peter J. Turnbaugh +11 more
TL;DR: Stable isotope-resolved metabolomics revealed that E. lenta uses acetate as a key carbon source while catabolizing arginine to generate ATP, traits which could be recapitulated in silico by the updated metabolic model.
Posted ContentDOI
CRISPR-Cas immunity repressed by a biofilm-activating pathway in Pseudomonas aeruginosa
Adair L. Borges,Bardo Castro,Sutharsan Govindarajan,Tina Solvik,Veronica Escalante,Joseph Bondy-Denomy +5 more
TL;DR: A forward genetic screen identifies a two-component system (KinB/AlgB), previously characterized in regulating Pseudomonas aeruginosa virulence and biofilm establishment, as a regulator of the biogenesis and activity of the Type I-F CRISPR-Cas system.