Cecilia Noecker

TL;DR: It is proposed that the gut microbiota regulates behaviors in mice via production of neuroactive metabolites, suggesting that gut-brain connections contribute to the pathophysiology of ASD.

TL;DR: A surprisingly large proportion of metabolite variation in the vaginal microbiome can be predicted based on species composition (including dramatic shifts associated with disease), identify putative mechanisms underlying these predictions, and evaluate the roles of individual bacterial species and genes.

TL;DR: Quantitative trait analysis identified mouse genetic trait loci (QTL) that impact the abundances of specific microbes that are implicated in arthritis, rheumatic disease and diabetes and Lactobacillales abundance was predictive of higher host T-helper cell counts, suggesting an important link between LactOBacillale and host adaptive immunity.

TL;DR: In this paper, the authors found that behavioral abnormalities could have distinct origins (host genetic versus microbial) may change the way we think about neurological disorders, and how to treat them.

TL;DR: The functionality of BURRITO is described, and illustrative examples of its utility for visualizing various trends in the relationship between the composition of taxa and functions in complex microbiomes are provided.