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Biao Wang
Researcher at University of California, San Francisco
Publications - 21
Citations - 1001
Biao Wang is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Thermogenesis & Brown adipose tissue. The author has an hindex of 10, co-authored 19 publications receiving 848 citations. Previous affiliations of Biao Wang include Cardiovascular Institute Hospital & University of California.
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Journal ArticleDOI
Induction of tumor angiogenesis by Slit-Robo signaling and inhibition of cancer growth by blocking Robo activity.
Biao Wang,Yang Xiao,Bei Bei Ding,Na Zhang,Na Zhang,Xiao bin Yuan,Lü Gui,Kai Xian Qian,Shumin Duan,Zhengjun Chen,Yi Rao,Jian Guo Geng +11 more
TL;DR: These findings demonstrate the angiogenic function of Slit-Robo signaling, reveal a mechanism in mediating the crosstalk between cancer cells and endothelial cells, and indicate the effectiveness of blocking this signaling pathway in treating cancers.
Journal ArticleDOI
A Hormone-Dependent Module Regulating Energy Balance
Biao Wang,Noel Moya,Sherry Niessen,Heather Hoover,Maria M. Mihaylova,Reuben J. Shaw,John R. Yates,Wolfgang H. Fischer,John B. Thomas,Marc Montminy +9 more
TL;DR: A hormone-regulated pathway that functions in parallel with the nutrient-sensing SIRT1 pathway to maintain energy balance is revealed, reflecting FOXO-dependent increases in lipolysis that deplete triglyceride stores.
Journal ArticleDOI
The Insulin-Regulated CREB Coactivator TORC Promotes Stress Resistance in Drosophila
Biao Wang,Jason Goode,Jennifer L. Best,Jodi Meltzer,Pablo E. Schilman,Jian Chen,Dan Garza,John B. Thomas,Marc Montminy +8 more
TL;DR: It is shown that starvation also triggers TORC activation in Drosophila, where it maintains energy balance through induction of CREB target genes in the brain to maintain energy balance.
Journal ArticleDOI
Neuronal energy-sensing pathway promotes energy balance by modulating disease tolerance
TL;DR: The results reveal a previously unidentified tolerance defense strategy involving a brain–gut pathway that maintains homeostasis through its effects on epithelial integrity in Drosophila.
Posted ContentDOI
Single-cell analysis of human primary prostate cancer reveals the heterogeneity of tumor-associated epithelial cell states
Hanbing Song,Weinstein Hn,Allegakoen P,Marc Wadsworth,Jin Xie,Hongbo Yang,Felix Feng,Peter R. Carroll,Biao Wang,Matthew R. Cooperberg,Alex K. Shalek,Huang Fw +11 more
TL;DR: A population of tumor-associated club cells that may act as progenitor cells and uncover heterogeneous cellular states in prostate epithelial cells marked by high androgen signaling states that are enriched in prostate cancer are identified.