V
Véronique Hubert
Researcher at Paris Descartes University
Publications - 28
Citations - 742
Véronique Hubert is an academic researcher from Paris Descartes University. The author has contributed to research in topics: Plasmodium falciparum & Malaria. The author has an hindex of 15, co-authored 27 publications receiving 671 citations. Previous affiliations of Véronique Hubert include University of Paris & Institut de recherche pour le développement.
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Journal ArticleDOI
Leishmania resistance to miltefosine associated with genetic marker.
Sandrine Cojean,Sandrine Houzé,Djamel Haouchine,Françoise Huteau,Sylvie Lariven,Véronique Hubert,Florence Michard,Christian Bories,Francine Pratlong,Jacques Le Bras,Philippe M. Loiseau,Sophie Matheron +11 more
TL;DR: During 2000–2010, serial Leishmania isolates obtained from an HIV-infected patient who was not responding to treatment showed a gradual decrease in in vitro miltefosine susceptibility, and a new single-nucleotide polymorphism (SNP), L832F, was identified, which might be a marker of milteFosine resistance in leishmaniasis.
Journal ArticleDOI
A Shared Asian Origin of the Triple-Mutant dhfr Allele in Plasmodium falciparum from Sites across Africa
Oumou Maïga,Oumou Maïga,Abdoulaye Djimde,Véronique Hubert,Emmanuelle Renard,Agneès Aubouy,Fred Kironde,Basile Nsimba,Kwadwo A. Koram,Ogobara K. Doumbo,Jacques Le Bras,Jérôme Clain +11 more
TL;DR: In this paper, a more comprehensive picture of the evolution of the triple-mutant dhfr allele in Africa is lacking, and the authors analyzed the diversity of the chromosomes bearing these alleles with four microsatellite markers closely linked to the dhfr gene and found that haplotypes were closely related to the predominant haplotype by mutation or recombination.
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Combined Deletions of pfhrp2 and pfhrp3 Genes Result in Plasmodium falciparum Malaria False-Negative Rapid Diagnostic Test
Sandrine Houzé,Sandrine Houzé,Véronique Hubert,Véronique Hubert,Gaëlle Le Pessec,Jacques Le Bras,Jacques Le Bras,Jérôme Clain,Jérôme Clain +8 more
TL;DR: A case of misdiagnosis of Plasmodium falciparum malaria from Brazil with negative PfHRP2-based rapid diagnostic tests (RDTs), leading to inappropriate case management is reported.
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Evaluation of the intra- and inter-specific genetic variability of Plasmodium lactate dehydrogenase
Arthur M. Talman,Arthur M. Talman,Linda Duval,Eric Legrand,Véronique Hubert,Seiha Yen,David Bell,Jacques Le Bras,Frédéric Ariey,Sandrine Houzé +9 more
TL;DR: The results indicate that antigen variability is unlikely to explain variability in performance of RDTs detecting pLDH from cases of P. falciparum, P. vivax or P. ovale, but may contribute to poor detection of Plasmodium ovale.
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Association of Microsatellite Variations of Plasmodium falciparum Na+/H+ Exchanger (Pfnhe-1) Gene with Reduced In Vitro Susceptibility to Quinine: Lack of Confirmation in Clinical Isolates from Africa
Valérie Andriantsoanirina,Didier Menard,Stéphane Rabearimanana,Véronique Hubert,Christiane Bouchier,Magali Tichit,Jacques Le Bras,Rémy Durand +7 more
TL;DR: It was concluded that the studied polymorphisms in Pfnhe-1 did not appear as valid molecular markers of in vitro susceptibility to quinine in P. falciparum isolates from Africa, but these results did not exclude the possibility of regional associations.