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Vicki E. Powers

Researcher at University of Toronto

Publications -  8
Citations -  780

Vicki E. Powers is an academic researcher from University of Toronto. The author has contributed to research in topics: Chromosome 22 & Chromosome. The author has an hindex of 8, co-authored 8 publications receiving 762 citations. Previous affiliations of Vicki E. Powers include Stanford University.

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Localization of the X inactivation centre on the human X chromosome in Xq13

TL;DR: An analysis of several rearranged human X chromosomes is reported and a minimal region of overlap is defined that is consistent with models invoking a single XIC and provide a molecular foothold for cloning and analysing the XIC region.
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Detection of restriction fragment length polymorphisms at the centromeres of human chromosomes by using chromosome-specific alpha satellite DNA probes: implications for development of centromere-based genetic linkage maps

TL;DR: Since the strategy is a general one, the alpha satellite family of DNA should provide a rich source of molecular variation in the human genome and should contribute to the development of centromere-based genetic linkage maps of human chromosomes.
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The β -subunit of follicle-stimulating hormone is deleted in patients with aniridia and Wilms' tumour, allowing a further definition of the WAGR locus

TL;DR: Close physical linkage between FSHB and the WAGR locus is demonstrated, suggest a gene order for the four deleted markers and exclude other markers tested from this region, as well as testing genomic DNA from the hybrids with chromosome 11-specific probes.
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Physical mapping of 60 DNA markers in the p21.1 → q21.3 region of the human X chromosome

TL;DR: Using a panel of human/rodent somatic cell hybrids and human lymphoblast lines segregating 18 different human X-chromosome rearrangements and deletions, 60 DNA markers are assigned to the physical map of the X chromosome from Xp21.1 to Xq21.3.
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Amplified DNA sequences in Y1 mouse adrenal tumor cells: association with double minutes and localization to a homogeneously staining chromosomal region.

TL;DR: These experiments provide direct evidence that the dm and HSRs in these Y1 cells are structurally related and further support the hypothesis that these chromosomal anomalies result from a process of gene amplification.