Vijay Yajnik

TL;DR: This study suggests that proper differentiation of epithelial cells is an important feature of colonic homeostasis because of its effect on the secretion of inflammatory cytokines.

TL;DR: Up to one-third of patients with CD have overall recurrence of disease after treatment with total colectomy and permanent ileostomy, suggesting there is need to develop algorithms for surveillance and management of this select subgroup of patients.

TL;DR: It is demonstrated that DOCK4 is underexpressed in MDS bone marrow samples and that the reduced expression is associated with decreased overall survival in patients, and a novel single-cell multispectral flow cytometry assay is developed for evaluation of disrupted F-actin filaments, which can be used for potential early detection of dysplastic cells in M DS.

TL;DR: There was no difference in risk of symptomatic perianal flares in patients with establishedPerianal CD delivering vaginally or through C-section, based on mode of delivery or between pregnant patients with CD and nonpregnant CD controls.

TL;DR: A multiomics analysis that integrated RNA microarray, total protein mass spectrometry, and phosphoproteomics analyses of tissues isolated from a mouse model of colitis identified Pak as a potential therapeutic target in IBD.