V
Vincent L. Chen
Researcher at University of Michigan
Publications - 83
Citations - 1411
Vincent L. Chen is an academic researcher from University of Michigan. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 17, co-authored 51 publications receiving 818 citations. Previous affiliations of Vincent L. Chen include Amherst College & Brigham and Women's Hospital.
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Journal ArticleDOI
17-Beta Hydroxysteroid Dehydrogenase 13 Is a Hepatic Retinol Dehydrogenase Associated With Histological Features of Nonalcoholic Fatty Liver Disease
Yanling Ma,Olga V. Belyaeva,Philip M. Brown,Koji Fujita,Katherine Valles,Suman Karki,Ynto S. de Boer,Christopher Koh,Yanhua Chen,Xiaomeng Du,Samuel K. Handelman,Vincent L. Chen,Elizabeth K. Speliotes,Cara Nestlerode,Emmanuel Thomas,David E. Kleiner,Joseph M. Zmuda,Arun J. Sanyal,Natalia Y. Kedishvili,T. Jake Liang,Yaron Rotman +20 more
TL;DR: The association of variants in HSD17B13 with specific features of NAFLD histology is demonstrated and the enzyme is identified as a lipid droplet–associated RDH; the data suggest that HSD 17B13 plays a role inNAFLD through its enzymatic activity.
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Predictors of Outcomes of COVID-19 in Patients with Chronic Liver Disease: US Multi-center Study.
Donghee Kim,Nia Adeniji,Nyann Latt,Sonal Kumar,Patricia P. Bloom,Elizabeth S. Aby,Elizabeth S. Aby,Ponni V. Perumalswami,Marina Roytman,Michael Li,Alexander S. Vogel,Andreea M. Catana,Kara Wegermann,Rotonya M. Carr,Costica Aloman,Vincent L. Chen,Atoosa Rabiee,Brett Sadowski,Veronica Nguyen,Winston Dunn,Kenneth D. Chavin,Kali Zhou,Blanca Lizaola-Mayo,Akshata Moghe,Jose D. Debes,Jose D. Debes,Tzu Hao Lee,Andrea D. Branch,Kathleen Viveiros,Walter W. Chan,David M. Chascsa,Paul Y. Kwo,Renumathy Dhanasekaran +32 more
TL;DR: The risk factors which predict higher overall mortality among patients with CLD and COVID-19 are ALD, decompensated cirrhosis and HCC.
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Efficacy of Fecal Microbiota Transplantation in Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis.
Dabo Xu,Vincent L. Chen,Calen A. Steiner,Jeffrey A. Berinstein,Shanti Eswaran,Akbar K. Waljee,Peter D.R. Higgins,Chung Owyang +7 more
TL;DR: Current evidence from RCTs does not suggest a benefit of FMT for global IBS symptoms and the Grading of Recommendations Assessment, Development and Evaluation quality of the body of evidence was very low.
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A Maternal Vaccine against Group B Streptococcus: Past, Present, and Future
TL;DR: The history of the design of maternal GBS vaccines is explored and how recent applications of genomics and immunology to vaccine design promise to further enhance the ability to develop more effective vaccines against this important disease is discussed.
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COVID-19 outcomes among solid organ transplant recipients: a case-control study
Pratima Sharma,Vincent L. Chen,Christopher Fung,Jonathan P. Troost,Vaiibhav N. Patel,Michael P. Combs,Silas P. Norman,Puneet Garg,Monica Colvin,Keith D. Aaronson,Christopher J. Sonnenday,Jonathan L. Golob,Emily C. Somers,Mona M. Doshi +13 more
TL;DR: HCQ for the treatment of COVID-19 among SOT recipients was associated with high mortality and therefore, its role as a treatment modality requires further scrutiny.