Showing papers by "Vinod Pullarkat published in 2006"
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TL;DR: The results suggest that RIC MUD HCT using PBSCs can be an effective treatment for older patients with MF.
35 citations
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UCLA Medical Center1, University of Minnesota2, City of Hope National Medical Center3, Memorial Sloan Kettering Cancer Center4, Washington University in St. Louis5, Baylor University Medical Center6, Wayne State University7, University of Texas MD Anderson Cancer Center8, University of Utah9, Duke University10, Loyola University Chicago11, Tufts Medical Center12, ViroPharma13, Fred Hutchinson Cancer Research Center14
TL;DR: Maribavir prophylaxis reduced the rate of CMV infection compared to placebo, with a favorable safety profile in this complex patient population, and Phase 3 studies of maribavIR in stem cell and solid organ transplant recipients are being planned.
6 citations
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TL;DR: This case illustrates that t-AML can rarely present as isolated extramedullary tumours, and the detection of specific chromosomal abnormalities in these myeloid sarcomas can be useful for risk assessment and guiding definitive therapy.
Abstract: Myeloid sarcomas are tumour masses of myeloid leukaemic cells at extramedullary sites. These tumours can, on occasion, occur without concurrent or antecedent leukaemia. Myeloid sarcomas have been described at unusual locations including the female genital tract. An unusual case of therapy-related acute myeloid leukaemia (t-AML) presenting as isolated monoblastic myeloid sarcoma of the uterus in a patient who had received adjuvant chemotherapy for breast cancer is presented. Fluorescence in situ hybridisation analysis performed on paraffin-wax-embedded tumour tissue revealed a mixed-lineage leukaemia (MLL) gene rearrangement, supporting the association of this malignancy with prior chemotherapy. This case illustrates that t-AML can rarely present as isolated extramedullary tumours, and the detection of specific chromosomal abnormalities in these myeloid sarcomas can be useful for risk assessment and guiding definitive therapy.
5 citations
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TL;DR: The result show the combination of sirolimus, tacrolimus and low-dose methotrexate is shown to be effective in preventing GVHD after unrelated donor hematopoietic stem cell transplantation.
2 citations