V
Violaine Moreau
Researcher at French Institute of Health and Medical Research
Publications - 57
Citations - 3501
Violaine Moreau is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Podosome & RHOA. The author has an hindex of 24, co-authored 52 publications receiving 3209 citations. Previous affiliations of Violaine Moreau include University of Bordeaux & Centre national de la recherche scientifique.
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Journal ArticleDOI
The microenvironment controls invadosome plasticity.
Julie Di Martino,Julie Di Martino,Elodie Henriet,Elodie Henriet,Zakaria Ezzoukhry,Zakaria Ezzoukhry,Jacky G. Goetz,Violaine Moreau,Violaine Moreau,Frédéric Saltel,Frédéric Saltel +10 more
TL;DR: This Commentary highlights recent findings regarding the role of type I collagen fibrils in inducing the formation of a new linear organisation of invadosomes and discusses invadosome plasticity, which depends on various factors, including the matrix microenvironment.
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Rnd3/RhoE Is down-regulated in hepatocellular carcinoma and controls cellular invasion.
Florence Grise,Florence Grise,Sandra Sena,Sandra Sena,Aurélien Bidaud-Meynard,Aurélien Bidaud-Meynard,Jessica Baud,Jean-Baptiste Hiriart,Jean-Baptiste Hiriart,Kassem Makki,Kassem Makki,Nathalie Dugot-Senant,Cathy Staedel,Paulette Bioulac-Sage,Paulette Bioulac-Sage,Jessica Zucman-Rossi,Jean Rosenbaum,Jean Rosenbaum,Violaine Moreau,Violaine Moreau +19 more
TL;DR: Rnd3 down‐regulation provides an invasive advantage to tumor hepatocytes, suggesting that RND3 might represent a metastasis suppressor gene in HCC.
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Extracellular matrix rigidity controls podosome induction in microvascular endothelial cells.
Amélie Juin,Emmanuelle Planus,Fabien Guillemot,Fabien Guillemot,Petra Horakova,Petra Horakova,Petra Horakova,Corinne Albiges-Rizo,Elisabeth Génot,Elisabeth Génot,Elisabeth Génot,Jean Rosenbaum,Jean Rosenbaum,Violaine Moreau,Violaine Moreau,Frédéric Saltel,Frédéric Saltel,Frédéric Saltel +17 more
TL;DR: This work focussed on liver sinusoidal endothelial cells (LSECs), fenestrated microvascular cells that play major roles in liver physiology and investigated the impact of matrix rigidity on podosome structures in LSECs.
Journal ArticleDOI
Cdc42 is required for membrane dependent actin polymerization in vitro
Violaine Moreau,Michael Way +1 more
TL;DR: The results demonstrate that membrane dependent actin polymerization, in contrast to Listeria stimulated actin filament assembly, is dependent on small GTPases of the Rho family.
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p190B RhoGAP regulates endothelial-cell-associated proteolysis through MT1-MMP and MMP2
Fabien Guegan,Florence Tatin,Thierry Leste-Lasserre,Guillaume Drutel,Elisabeth Génot,Violaine Moreau +5 more
TL;DR: It is concluded that the two p190 RhoGAP isoforms play distinct roles in endothelial cells and an unsuspected role for p190B in the expression of the two collaborative proteases MT1-MMP and MMP2, thereby affecting matrix remodelling and angiogenesis.