V
Vito Boido
Researcher at University of Genoa
Publications - 36
Citations - 906
Vito Boido is an academic researcher from University of Genoa. The author has contributed to research in topics: Virus & Clofazimine. The author has an hindex of 16, co-authored 36 publications receiving 812 citations.
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Journal ArticleDOI
Antiviral activity of benzimidazole derivatives. II. Antiviral activity of 2-phenylbenzimidazole derivatives.
Michele Tonelli,Matteo Simone,Bruno Tasso,Federica Novelli,Vito Boido,Fabio Sparatore,Giuseppe Paglietti,Sabrina Pricl,Gabriele Giliberti,Sylvain Blois,Cristina Ibba,Giuseppina Sanna,Roberta Loddo,Paolo La Colla +13 more
TL;DR: The considered compounds represent attractive leads for the development of antiviral agents against poxviruses, pestiviruses and even HCV, which are important human and veterinary pathogens.
Journal ArticleDOI
Cytisine derivatives as ligands for neuronal nicotine receptors and with various pharmacological activities.
TL;DR: A systematic structural modification of cytisine was undertaken in order to obtain compounds of potential therapeutic interest at peripheral as well as central level, with a particular concern for achieving nAChR subtype selective ligands.
Journal ArticleDOI
Antiviral and cytotoxic activities of aminoarylazo compounds and aryltriazene derivatives
Michele Tonelli,I. Vazzana,Bruno Tasso,Vito Boido,Fabio Sparatore,Maurizio Fermeglia,Maria Silvia Paneni,Paola Posocco,Sabrina Pricl,Paolo La Colla,Cristina Ibba,Barbara Secci,Gabriella Collu,Roberta Loddo +13 more
TL;DR: Seven aminoazocompounds and 27 aryltriazene derivatives exhibited antiviral activity, sometimes of high level, against one or more viruses, while a marked activity against BVDV and YFV was prevailing among the former compounds.
Journal ArticleDOI
Antiviral Activity of Benzimidazole Derivatives. I. Antiviral Activity of 1-Substituted-2-[(Benzotriazol-1/2-yl)methyl]benzimidazoles
Michele Tonelli,Giuseppe Paglietti,Vito Boido,Fabio Sparatore,Fabio Marongiu,Esther Marongiu,Paolo La Colla,Roberta Loddo +7 more
TL;DR: Most compounds exhibited potent activity against RSV, with EC50 values as low as 20 nM, and some compounds, in particular when bearing a (quinolizidin‐1‐yl)alkyl residue, were also moderately active against BVDV, YFV, and CVB2.
Journal ArticleDOI
Quinolizidinyl derivatives of bi- and tricyclic systems as potent inhibitors of acetyl- and butyrylcholinesterase with potential in Alzheimer's disease
Bruno Tasso,Marco Catto,Orazio Nicolotti,Federica Novelli,Michele Tonelli,Ilenia Giangreco,Leonardo Pisani,Anna Sparatore,Vito Boido,Angelo Carotti,Fabio Sparatore +10 more
TL;DR: Several quinolizidinyl derivatives of bi- and tricyclic (hetero)aromatic systems were studied as dual, or BChE-selective inhibitors, and may represent hits for the development of interesting single-entity multi-target drugs.