W
W. Peter Vandertop
Researcher at University of Amsterdam
Publications - 192
Citations - 8800
W. Peter Vandertop is an academic researcher from University of Amsterdam. The author has contributed to research in topics: Subarachnoid hemorrhage & Glioma. The author has an hindex of 44, co-authored 165 publications receiving 7355 citations. Previous affiliations of W. Peter Vandertop include VU University Medical Center & VU University Amsterdam.
Papers
More filters
Journal ArticleDOI
Treatment of hydrocephalus determined by the European Orbis Sigma Valve II survey: a multicenter prospective 5-year shunt survival study in children and adults in whom a flow-regulating shunt was used
Patrick W Hanlo,Giuseppe Cinalli,W. Peter Vandertop,Joop A J Faber,Lars Bøgeskov,Svend Erik Børgesen,Jürgen Boschert,Paul Chumas,Hans Eder,Ian K. Pople,Willy Serlo,Eckehard Vitzthum +11 more
TL;DR: The authors demonstrate the effectiveness of flow regulation in the treatment of hydrocephalus both in children and in adults as well as comparing favorably with rates cited in other recently published series.
Journal ArticleDOI
Effects of the Selective MPS1 Inhibitor MPS1-IN-3 on Glioblastoma Sensitivity to Antimitotic Drugs
Bakhos A. Tannous,Mariam Kerami,Petra van der Stoop,Nicholas Kwiatkowski,Jinhua Wang,Wenjun Zhou,Almuth F. Kessler,Grant K. Lewandrowski,Lotte Hiddingh,Nik Sol,Tonny Lagerweij,Laurine E. Wedekind,Johanna M. Niers,Marco Barazas,R. Jonas A. Nilsson,Dirk Geerts,Philip C. De Witt Hamer,Carsten Hagemann,W. Peter Vandertop,Olaf van Tellingen,David P. Noske,Nathanael S. Gray,Thomas Wurdinger +22 more
TL;DR: It is demonstrated that MPS1, a putative therapeutic target in glioblastoma, can be selectively inhibited by M PS1-IN-3 sensitizing gliOBlastoma cells to antimitotic drugs.
Journal ArticleDOI
Myc-associated zinc finger protein (MAZ) is regulated by miR-125b and mediates VEGF-induced angiogenesis in glioblastoma
Michiel Smits,Thomas Wurdinger,Bert van het Hof,Joost A. R. Drexhage,Dirk Geerts,Pieter Wesseling,David P. Noske,W. Peter Vandertop,Helga E. de Vries,Arie Reijerkerk +9 more
TL;DR: It is reported that miR‐125b is down‐regulated in glioblastoma‐associated endothelial cells, resulting in increased expression of its target, myc‐associated zinc finger protein (MAZ), a transcription factor that regulates VEGF.
Journal ArticleDOI
High risk of acute deterioration in patients harboring symptomatic colloid cysts of the third ventricle.
Philip C. De Witt Hamer,Marco J. T. Verstegen,Rob J De Haan,W. Peter Vandertop,Ralph T W M Thomeer,Jan Jacob Mooij,Wouter R. van Furth +6 more
TL;DR: The risk of acute deterioration in a symptomatic patient with a colloid cyst in The Netherlands is estimated to be 34%, and the estimated risk for an asymptomatic patients with an incidental colloid Cyst is significantly lower.
Journal ArticleDOI
Cyclophosphamide Increases Transgene Expression Mediated by an Oncolytic Adenovirus in Glioma-Bearing Mice Monitored by Bioluminescence Imaging
Martine L.M. Lamfers,Martine L.M. Lamfers,Giulia Fulci,Giulia Fulci,Davide Gianni,Yi Tang,Kazuhiko Kurozumi,Balveen Kaur,Sharif Moeniralm,Yoshinaga Saeki,Yoshinaga Saeki,Jan E. Carette,Ralph Weissleder,W. Peter Vandertop,Victor W. van Beusechem,Clemens M F Dirven,E. Antonio Chiocca,E. Antonio Chiocca +17 more
TL;DR: It is demonstrated that transgene expression and viral replication decrease rapidly after intratumoral injection of oncolytic adenovirus in mouse brains and that treatment with the immunomodulator CPA prolongs viral-mediated gene expression.