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Warren M. Zapol
Researcher at Harvard University
Publications - 423
Citations - 26610
Warren M. Zapol is an academic researcher from Harvard University. The author has contributed to research in topics: Nitric oxide & Pulmonary hypertension. The author has an hindex of 81, co-authored 418 publications receiving 25338 citations. Previous affiliations of Warren M. Zapol include Brigham and Women's Hospital & University of British Columbia.
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Patent
Use of NO for treating persistent pulmonary hypertension of the newborn
Warren M. Zapol,Claes Frostell +1 more
Journal ArticleDOI
Acute cor pulmonale in acute respiratory distress syndrome: a dreaded complication of the past?
Journal ArticleDOI
Nitric oxide inhalation in the intensive care unit
TL;DR: In an injured lung with pulmonary hypertension, inhaled NO produces local vasodilation of wellventilated lung units and may 'steal' blood flow away from unventilated regions, which reduces intrapulmonary shunting and may improve systemic arterial oxygenation.
Journal ArticleDOI
Nitric oxide regulates pulmonary vascular smooth muscle cell expression of the inducible cAMP early repressor gene
Andrea U. Steinbicker,Heling Liu,Kim Jiramongkolchai,Rajeev Malhotra,Elizabeth Y. Choe,Cornelius J. Busch,Amanda R. Graveline,Sonya M. Kao,Yasuko Nagasaka,Fumito Ichinose,Emmanuel S. Buys,Peter Brouckaert,Warren M. Zapol,Kenneth D. Bloch +13 more
TL;DR: The results suggest that induction of ICER gene expression by NO requires both CREB phosphorylation and Ca(2+) signaling, highlighting a novel cross-talk mechanism between cGMP and cAMP signaling pathways.