Warren M. Zapol

TL;DR: Thoracotomy and pulmonary resection produce a marked reduction of active diaphragmatic shortening, which is not reversed by thoracic epidural anesthesia despite improvement of other indices of respiratory function.

TL;DR: Breathing Nitric oxide leads to the rapid accumulation of a variety of nitric oxide metabolites in blood and tissues, contributing to the ability of brief periods of nitrics oxide inhalation to provide cardioprotection against ischemia–reperfusion injury.

TL;DR: It is shown that breathing normobaric 11% O2 in mice with late-stage encephalopathy reverses their established neurological disease, evidenced by improved behavior, circulating disease biomarkers, and survival rates.

TL;DR: A submersible dual-wavelength laser near-infrared spectrophotometer capable of measuring MbO2 saturation in swimming muscle was implanted on the surface of the latissimus dorsi of five subadult male Weddell seals released into a captive breathing hole near Ross Island, Antarctica and showed no correlation between the power consumed by swimming and the desaturation rate.

TL;DR: It is shown by morphometric and hemodynamic techniques that exposure to hyperoxia at normobaric pressure causes rapid structural remodeling of rat pulmonary arteries and pulmonary hypertension.