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Warren M. Zapol
Researcher at Harvard University
Publications - 423
Citations - 26610
Warren M. Zapol is an academic researcher from Harvard University. The author has contributed to research in topics: Nitric oxide & Pulmonary hypertension. The author has an hindex of 81, co-authored 418 publications receiving 25338 citations. Previous affiliations of Warren M. Zapol include Brigham and Women's Hospital & University of British Columbia.
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Journal ArticleDOI
Congenital NOS2 Deficiency Protects Mice from LPS-induced Hyporesponsiveness to Inhaled Nitric Oxide
TL;DR: It is suggested that NO, plus other lipopolysaccharide-induced products, are necessary to impair responsiveness to inhaled NO in a murine sepsis model and prolonged NO breathing, without endotoxin, does not impair vasodilation in response to subsequent NO inhalation.
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Volotrauma and the Intravenous Oxygenator in Patients with Adult Respiratory Distress Syndrome
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Inhaled Nitric Oxide as an Adjunctive Treatment for Cerebral Malaria in Children: A Phase II Randomized Open-Label Clinical Trial.
Juliet Mwanga-Amumpaire,Ryan W. Carroll,Elisabeth Baudin,Elisabeth Kemigisha,Dorah Nampijja,Kenneth Mworozi,Data Santorino,Dan Nyehangane,Daniel I. Nathan,Pierre De Beaudrap,Jean-François Etard,Martin Feelisch,Bernadette O. Fernandez,Annie Berssenbrugge,David R. Bangsberg,Kenneth D. Bloch,Yap Boum,Warren M. Zapol +17 more
TL;DR: Treatment with inhaled nitric oxide as an adjuvant therapy for pediatric patients with cerebral malaria for 48 hours did not result in a significant difference in plasma Angiopoietin-1 levels when compared with placebo in a phase II open-label clinical trial.
Journal Article
Protamine reactions, explosive mediator release, and pulmonary vasoconstriction.
Journal ArticleDOI
Adverse effects of hemorrhagic shock resuscitation with stored blood are ameliorated by inhaled nitric oxide in lambs
David M. Baron,Arkadi Beloiartsev,Akito Nakagawa,Trejeeve Martyn,Christopher P. Stowell,Rajeev Malhotra,Claire Mayeur,Kenneth D. Bloch,Warren M. Zapol +8 more
TL;DR: It is suggested that resuscitation of lambs from hemorrhagic shock with autologous stored RBCs induces pulmonary hypertension and inflammation, which can be ameliorated by breathing nitric oxide.