Wei Li

TL;DR: In this article, the identity of EBI macrophages has thus far remained elusive, but it is known that Epor-eGFP is essential for erythropoiesis and Epor is expressed in numerous nonerythroid cells.

TL;DR: It is shown that TET2 deficiency leads initially to stem cell factor-dependent hyperproliferation and impaired differentiation of human colony-forming unit-erythroid (CFU-E) cells, which were reversed by a c-Kit inhibitor, and previously unknown mechanisms by which deficiency of TET1 contributes to ineffective erythropoiesis are uncovered.

TL;DR: It is Documented that SF3B1 knockdown in human CD34+ cells leads to increased apoptosis and cell cycle arrest of early-stage erythroid cells and generation of abnormally nucleated late-Stage erythroblasts and these findings have implications for improved understanding of ineffective erythropoiesis in MDS patients with SF3 B1 mutations.

TL;DR: In this article, the role of histone deacetylases (HDACs) in mammalian erythropoiesis remains to be fully defined, however, it is known that HDACs have diverse functions in a wide range of biological processes.

TL;DR: These findings imply that 4.1N, βII spectrin and ankyrin G are structural components of the lateral membrane skeleton and that this skeleton plays an essential role in the assembly of a fully functional lateral membrane.