Xiaoli Qu

TL;DR: This review provides concise insights into the recent development of CDs in nanomedicine research, including preparation and functionalization processes, and a few critical applications are highlighted, such as antibacterial applications, chemotherapy, and therapeutics.

TL;DR: Carbon dots (CDs) are currently attracting a lot of interest in biological fields owing to their fluorescent properties, high photostability, biocompatibility and low toxicity as discussed by the authors .

TL;DR: It is shown here that TET2 and TET3 but not TET1 are expressed in human erythroid cells, and the role of these proteins in erythropoiesis is explored, to provide new insights into their role in regulating human ERYthroid differentiation at distinct stages of development.

TL;DR: It is shown that TET2 deficiency leads initially to stem cell factor-dependent hyperproliferation and impaired differentiation of human colony-forming unit-erythroid (CFU-E) cells, which were reversed by a c-Kit inhibitor, and previously unknown mechanisms by which deficiency of TET1 contributes to ineffective erythropoiesis are uncovered.

TL;DR: In cultured cells, the methylation of the −100 CpG dinucleotides of the POMC promoter blocked both the formation of Sp1–promoter complex and the leptin-induced activation of PomC, suggesting that this CLA-mediated hypermethylation may contribute, at least in part, to the metabolic disorders.