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Wendy J. van Zuylen
Researcher at University of New South Wales
Publications - 24
Citations - 1584
Wendy J. van Zuylen is an academic researcher from University of New South Wales. The author has contributed to research in topics: Human cytomegalovirus & Congenital cytomegalovirus infection. The author has an hindex of 14, co-authored 23 publications receiving 1301 citations. Previous affiliations of Wendy J. van Zuylen include Université de Montréal & QIMR Berghofer Medical Research Institute.
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Journal ArticleDOI
Congenital cytomegalovirus infection in pregnancy and the neonate: consensus recommendations for prevention, diagnosis, and therapy.
William D. Rawlinson,Suresh B. Boppana,Karen B. Fowler,David W. Kimberlin,Tiziana Lazzarotto,Sophie Alain,Kate Daly,Sara Menlove Doutre,Laura Gibson,Michelle L. Giles,Janelle Greenlee,Stuart T. Hamilton,Gail J. Demmler Harrison,Lisa Hui,Lisa Hui,Cheryl A Jones,Cheryl A Jones,Pamela Palasanthiran,Pamela Palasanthiran,Mark R. Schleiss,Antonia W. Shand,Antonia W. Shand,Wendy J. van Zuylen +22 more
TL;DR: The International Congenital Cytomegalovirus Recommendations Group (ICG) as discussed by the authors was formed in 2015 to provide recommendations for prevention, diagnosis, and treatment of CG infection.
Journal ArticleDOI
LPS regulates proinflammatory gene expression in macrophages by altering histone deacetylase expression
Hnin Thanda Aung,Kate Schroder,Stewart R. Himes,Kristian Brion,Wendy J. van Zuylen,Angela Trieu,Harukazu Suzuki,Yoshihide Hayashizaki,David A. Hume,Matthew J. Sweet,Timothy Ravasi +10 more
TL;DR: It is shown that LPS regulated several members of the histone deacetylase (HDAC) family at the mRNA level in murine bone marrow‐derived macrophages (BMM), and HDACs act as potent and selective negative regulators of proinflammatory gene expression and act to prevent excessive inflammatory responses inmacrophages.
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High resolution structures of highly bulged viral epitopes bound to major histocompatibility complex class I. Implications for T-cell receptor engagement and T-cell immunodominance
Fleur Elizabeth Tynan,Natalie A. Borg,John J. Miles,Travis Clarke Beddoe,Diah Elhassen,Sharon L. Silins,Wendy J. van Zuylen,Anthony W. Purcell,Lars Kjer-Nielsen,James McCluskey,Scott R. Burrows,Jamie Rossjohn +11 more
TL;DR: An HLA-B*3508-restricted cytotoxic T lymphocyte response to a 13-mer viral epitope (LPEPLPQGQLTAY) is described, which generated a biased T-cell response.
Journal ArticleDOI
Congenital cytomegalovirus infection in pregnancy: a review of prevalence, clinical features, diagnosis and prevention
Zin Naing,Gillian M. Scott,Antonia W. Shand,Stuart T. Hamilton,Wendy J. van Zuylen,James Basha,Beverly Hall,Maria E. Craig,Maria E. Craig,William D. Rawlinson +9 more
TL;DR: Recognition of the importance of CMV in pregnancy and in neonates is increasingly needed, particularly as therapeutic and preventive interventions expand for this serious problem.
Journal ArticleDOI
Macrophage Activation and Differentiation Signals Regulate Schlafen-4 Gene Expression: Evidence for Schlafen-4 as a Modulator of Myelopoiesis
Wendy J. van Zuylen,Valerie Garceau,Adi Idris,Kate Schroder,Katharine M. Irvine,Jane E. Lattin,Dmitry A. Ovchinnikov,Andrew C. Perkins,Andrew D. Cook,John A. Hamilton,Paul J. Hertzog,Katryn J. Stacey,Stuart Kellie,David A. Hume,Matthew J. Sweet +14 more
TL;DR: It is hypothesised that the down-regulation of Slfn4 gene expression during macrophage differentiation is a necessary step in development of this lineage of mice and therefore perturbs myelopoiesis.