K
Katharine M. Irvine
Researcher at University of Queensland
Publications - 127
Citations - 6370
Katharine M. Irvine is an academic researcher from University of Queensland. The author has contributed to research in topics: Macrophage & Fibrosis. The author has an hindex of 35, co-authored 110 publications receiving 5262 citations. Previous affiliations of Katharine M. Irvine include Cooperative Research Centre & Translational Research Institute.
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Journal ArticleDOI
The regulated retrotransposon transcriptome of mammalian cells.
Geoffrey J. Faulkner,Yasumasa Kimura,Carsten O. Daub,Shivangi Wani,Charles Plessy,Katharine M. Irvine,Kate Schroder,Nicole Cloonan,Anita L Steptoe,Timo Lassmann,Kazunori Waki,Nadine Hornig,Takahiro Arakawa,Hazuki Takahashi,Jun Kawai,Alistair R. R. Forrest,Harukazu Suzuki,Yoshihide Hayashizaki,David A. Hume,Valerio Orlando,Sean M. Grimmond,Piero Carninci +21 more
TL;DR: It is reported that 6–30% of cap-selected mouse and human RNA transcripts initiate within repetitive elements, and it is concluded that retrotransposon transcription has a key influence upon the transcriptional output of the mammalian genome.
Journal ArticleDOI
The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line
Harukazu Suzuki,Alistair R. R. Forrest,Erik van Nimwegen,Carsten O. Daub,Piotr J. Balwierz,Katharine M. Irvine,Timo Lassmann,Timothy Ravasi,Yuki Hasegawa,Michiel J. L. de Hoon,Shintaro Katayama,Kate Schroder,Piero Carninci,Yasuhiro Tomaru,Mutsumi Kanamori-Katayama,Atsutaka Kubosaki,Altuna Akalin,Yoshinari Ando,Erik Arner,Maki Asada,Hiroshi Asahara,Timothy L. Bailey,Vladimir B. Bajic,Denis C. Bauer,Anthony G Beckhouse,Nicolas Bertin,Johan Björkegren,Frank Brombacher,Erika Bulger,Alistair M. Chalk,Joe Chiba,Nicole Cloonan,Adam Dawe,Josée Dostie,Pär G. Engström,Magbubah Essack,Geoffrey J. Faulkner,J. Lynn Fink,David Fredman,Ko Fujimori,Masaaki Furuno,Takashi Gojobori,Julian Gough,Sean M. Grimmond,Mika Gustafsson,Megumi Hashimoto,Takehiro Hashimoto,Mariko Hatakeyama,Susanne Heinzel,Winston Hide,Winston Hide,Oliver Hofmann,Oliver Hofmann,Michael Hörnquist,Lukasz Huminiecki,Kazuho Ikeo,Naoko Imamoto,Satoshi Inoue,Yusuke Inoue,Ryoko Ishihara,Takao Iwayanagi,Anders Jacobsen,Mandeep Kaur,Hideya Kawaji,Markus C. Kerr,Ryuichiro Kimura,Syuhei Kimura,Yasumasa Kimura,Hiroaki Kitano,Hisashi Koga,Toshio Kojima,Shinji Kondo,Takeshi Konno,Anders Krogh,Adele Kruger,Ajit Kumar,Boris Lenhard,Andreas Lennartsson,Morten Lindow,Marina Lizio,Cameron Ross MacPherson,Norihiro Maeda,Christopher G. Maher,Monique Maqungo,Jessica C. Mar,Nicholas Matigian,Hideo Matsuda,John S. Mattick,Stuart Meier,Sei Miyamoto,Etsuko Miyamoto-Sato,Kazuhiko Nakabayashi,Yutaka Nakachi,Mika Nakano,Sanne Nygaard,Toshitsugu Okayama,Yasushi Okazaki,Haruka Okuda-Yabukami,Valerio Orlando,Jun Otomo,Mikhail Pachkov,Nikolai Petrovsky,Charles Plessy,John Quackenbush,Aleksandar Radovanovic,Michael Rehli,Rintaro Saito,Albin Sandelin,Sebastian Schmeier,Christian Schönbach,Ariel S. Schwartz,Colin A. Semple,Miho Sera,Jessica Severin,Katsuhiko Shirahige,Cas Simons,Georges St. Laurent,Masanori Suzuki,Takahiro Suzuki,Matthew J. Sweet,Ryan J. Taft,Shizu Takeda,Yoichi Takenaka,Kai Tan,Martin S. Taylor,Rohan D. Teasdale,Jesper Tegnér,Jesper Tegnér,Sarah A. Teichmann,Eivind Valen,Claes Wahlestedt,Kazunori Waki,Andrew Waterhouse,Christine A. Wells,Ole Winther,Linda Wu,Kazumi Yamaguchi,Hiroshi Yanagawa,Jun Yasuda,Mihaela Zavolan,David A. Hume,Takahiro Arakawa,Shiro Fukuda,Kengo Imamura,Chikatoshi Kai,Ai Kaiho,Tsugumi Kawashima,Chika Kawazu,Yayoi Kitazume,Miki Kojima,Hisashi Miura,Kayoko Murakami,Mitsuyoshi Murata,Noriko Ninomiya,Hiromi Nishiyori,Shohei Noma,Chihiro Ogawa,Takuma Sano,Christophe Simon,Michihira Tagami,Yukari Takahashi,Jun Kawai,Yoshihide Hayashizaki +162 more
TL;DR: The results indicate that cellular states are constrained by complex networks involving both positive and negative regulatory interactions among substantial numbers of transcription factors and that no single transcription factor is both necessary and sufficient to drive the differentiation process.
Journal ArticleDOI
Histone deacetylases as regulators of inflammation and immunity.
TL;DR: Current understanding of innate and adaptive immune pathways that are regulated by classical HDAC enzymes are reviewed to provide a rationale for targeting (or not targeting) individualHDAC enzymes with inhibitors for future immune-related applications.
Journal ArticleDOI
Tiny RNAs associated with transcription start sites in animals.
Ryan J. Taft,Evgeny A. Glazov,Nicole Cloonan,Cas Simons,Stuart Stephen,Geoffrey J. Faulkner,Timo Lassmann,Alistair R. R. Forrest,Sean M. Grimmond,Kate Schroder,Katharine M. Irvine,Takahiro Arakawa,Mari M. Nakamura,Atsutaka Kubosaki,Kengo Hayashida,Chika Kawazu,Mitsuyoshi Murata,Hiromi Nishiyori,Shiro Fukuda,Jun Kawai,Carsten O. Daub,David A. Hume,David A. Hume,Harukazu Suzuki,Valerio Orlando,Piero Carninci,Yoshihide Hayashizaki,John S. Mattick +27 more
TL;DR: These tiny RNAs with a modal length of 18 nt that map within −60 to +120 nt of transcription start sites (TSSs) in human, chicken and Drosophila suggest that tiRNAs may be a general feature of transcription in metazoa and possibly all eukaryotes.
Journal Article
Tiny RNAs associated with transcription start sites in animals (vol 41, pg 572, 2009)
Ryan J. Taft,Evgeny A. Glazov,Nicole Cloonan,Cas Simons,Stuart Stephen,Geoffrey J. Faulkner,Timo Lassmann,Arr Forrest,Sean M. Grimmond,Kate Schroder,Katharine M. Irvine,Taku Arakawa,Masayuki Nakamura,Atsutaka Kubosaki,Kengo Hayashida,Chika Kawazu,Mitsuyoshi Murata,Hiromi Nishiyori,Shiro Fukuda,Jun Kawai,Carsten O. Daub,David A. Hume,Harukazu Suzuki,Orlando,Piero Carninci,Yoshihide Hayashizaki,John S. Mattick +26 more