WenFang Wang

TL;DR: The resemblance between the tooth and nail phenotype in the human family and that ofMsx1-knockout mice strongly supports the conclusions that a nonsense mutation in MSX1 causes TNS and that Msx1 is critical for both Tooth and nail development.

TL;DR: In this paper, a yeast two-hybrid system was used to identify a groucho homologue, Grg5, as a Runx2-interacting protein, and by analyses of postnatal growth in mice, it was shown that Grg 5 and Runx 2 interact genetically.

TL;DR: It is demonstrated that parathyroid hormone stimulation of RANKL in mice is not affected by a significant reduction in the number of osteoblasts and commitment to the osteoblast lineage is not a requirement for RankL gene transcription in fibroblastic stromal cells, which suggests responsiveness of this gene to specific hormones via control of their receptors may be enhanced.

TL;DR: Investigating the mechanisms of these phenomena in prediabetic Ncb5or−/− mice suggests that increased FFA accumulation and catabolism and oxidative stress are major consequences of NCB5or deficiency in liver.

TL;DR: The F plasmid PifA protein, known to be the cause of F exclusion of bacteriophage T7, is shown to be a membrane-associated protein and the Escherichia coli FxsAprotein, which, at higher concentrations than found in wild-type cells, protects T7 from exclusion, is shows to interact with PifC.