William Silversmith

TL;DR: A new kind of digital resource that encompasses almost 400 ganglion cells from a single patch of mouse retina is presented, revealing two aspects of the retina's inner plexiform layer: an arbor segregation principle governing structure along the light axis and a density conservation Principle governing structure in the tangential plane.

TL;DR: FlyWire, an online community for proofreading neural circuits in a fly brain, is presented and it is demonstrated how FlyWire enables circuit analysis by reconstructing and analysing the connectome of mechanosensory neurons.

TL;DR: In this paper, the authors present a unique functional connectomics dataset that contains calcium imaging of an estimated 75,000 neurons from primary visual cortex (VISp) and three higher visual areas (VISrl, VISal and VISlm), that were recorded while a mouse viewed natural movies and parametric stimuli.

TL;DR: It is shown that synapse size, when restricted to synapses between L2/3 pyramidal cells, is well-modeled by the sum of a binary variable and an analog variable drawn from a log-normal distribution, which is consistent with most neural network models of learning.

TL;DR: In this article , a semi-automated reconstruction of L2/3 mouse primary visual cortex from ∼250 × 140 × 90 μm3 of electron microscopic images, including pyramidal and non-pyramidal neurons, was presented.