W
William T. Butler
Researcher at University of Texas Health Science Center at Houston
Publications - 117
Citations - 9589
William T. Butler is an academic researcher from University of Texas Health Science Center at Houston. The author has contributed to research in topics: Dentin sialoprotein & Osteopontin. The author has an hindex of 57, co-authored 117 publications receiving 9362 citations. Previous affiliations of William T. Butler include University of Texas Health Science Center at San Antonio & Northwestern University.
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Journal ArticleDOI
The nature and significance of osteopontin
TL;DR: This conclusion is supported by a number of studies showing that the protein promotes attachment and spreading of fibroblasts and osteoblasts to substratum, and that this attachment is inhibited by RGD-containing peptides.
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Post-translational modifications of sibling proteins and their roles in osteogenesis and dentinogenesis.
TL;DR: It is envisioned that the proteolytic processing of DMP1 and DSPP may be an activation process that plays a significant, crucial role in osteogenesis and dentinogenesis, and that a failure in this processing would cause defective mineralization in bone and dentIn, as observed in X-linked hypophosphatemic rickets.
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Isolation, characterization, and biosynthesis of a phosphorylated glycoprotein from rat bone.
Charles W. Prince,T. Oosawa,William T. Butler,Milan Tomana,A S Bhown,M Bhown,Ralph E. Schrohenloher +6 more
TL;DR: A phosphorylated glycoprotein was purified from the mixture of proteins extracted by demineralization of rat bone with 0.5 M EDTA in 4 M guanidinium chloride and showed a high level of purity.
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Effects of Corticosteroids on Immunity in Man I. DECREASED SERUM IgG CONCENTRATION CAUSED BY 3 OR 5 DAYS OF HIGH DOSES OF METHYLPREDNISOLONE
TL;DR: In this article, the effects of methylprednisolone on immune mechanisms in the absence of other immunosuppressive agents or immunologically mediated diseases were studied and it was found that 86% of treated volunteers had significant decreases in the concentrations of serum IgG.
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Importance of Phosphorylation for Osteopontin Regulation of Biomineralization
Arne Gericke,Chunlin Qin,Lyudmila Spevak,Yukiji K. Fujimoto,William T. Butler,Esben S. Sørensen,Adele L. Boskey,Adele L. Boskey +7 more
TL;DR: The hypotheses that the interaction of OPN with HA is determined by the extent of protein phosphorylation and that this interaction regulates the mineralization process are tested are tested.