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Chunlin Qin
Researcher at Texas A&M University
Publications - 134
Citations - 6430
Chunlin Qin is an academic researcher from Texas A&M University. The author has contributed to research in topics: Dentin & DMP1. The author has an hindex of 41, co-authored 132 publications receiving 5805 citations. Previous affiliations of Chunlin Qin include Texas A&M Health Science Center & Baylor College of Medicine.
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Journal ArticleDOI
Post-translational modifications of sibling proteins and their roles in osteogenesis and dentinogenesis.
TL;DR: It is envisioned that the proteolytic processing of DMP1 and DSPP may be an activation process that plays a significant, crucial role in osteogenesis and dentinogenesis, and that a failure in this processing would cause defective mineralization in bone and dentIn, as observed in X-linked hypophosphatemic rickets.
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Normal and disease-related biological functions of Twist1 and underlying molecular mechanisms.
TL;DR: Understanding of the mechanisms by which Twist1 promotes metastasis and identification of Twist1 functional modulators may hold promise for developing new strategies to inhibit EMT and cancer metastasis.
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Importance of Phosphorylation for Osteopontin Regulation of Biomineralization
Arne Gericke,Chunlin Qin,Lyudmila Spevak,Yukiji K. Fujimoto,William T. Butler,Esben S. Sørensen,Adele L. Boskey,Adele L. Boskey +7 more
TL;DR: The hypotheses that the interaction of OPN with HA is determined by the extent of protein phosphorylation and that this interaction regulates the mineralization process are tested are tested.
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The Expression of Dentin Sialophosphoprotein Gene in Bone
Chunlin Qin,Jan C. Brunn,Elizabeth Cadena,Amy L. Ridall,Hidetsugu Tsujigiwa,Hitoshi Nagatsuka,Noriyuki Nagai,William T. Butler +7 more
TL;DR: Results indicated that the dspp gene is expressed at a lower level in bone than in dentin and odontoblasts, and that dramatically different regulatory mechanisms governing DSPP expression are involved in the bone and dentin.
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Matrix Macromolecules in Hard Tissues Control the Nucleation and Hierarchical Assembly of Hydroxyapatite
TL;DR: It is reported that organic constituents of bones and teeth, namely type I collagen and dentin matrix protein 1 (DMP1), are effective crystal modulators and control nucleation of calcium phosphate polymorphs and the assembly of hierarchically ordered crystalline composite material.