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Xavier Bellés

Researcher at Pompeu Fabra University

Publications -  175
Citations -  7057

Xavier Bellés is an academic researcher from Pompeu Fabra University. The author has contributed to research in topics: Juvenile hormone & Metamorphosis. The author has an hindex of 46, co-authored 168 publications receiving 6175 citations. Previous affiliations of Xavier Bellés include Spanish National Research Council.

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Beyond Drosophila: RNAi In Vivo and Functional Genomics in Insects

TL;DR: The increasing availability of insect genomes has revealed a large number of genes with unknown functions and the resulting problem of how to discover these functions, and the RNA interference technique, which generates loss-of-function phenotypes by depletion of a chosen transcript, can help to overcome this challenge.
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The mevalonate pathway and the synthesis of juvenile hormone in insects.

TL;DR: The data suggest that the mevalonate pathway in insects can best be interpreted in terms of coordinated regulation, in which regulators act in parallel to a number of enzymes, as occurs in the cholesterol-driven pathway in vertebrates.
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Molecular basis of juvenile hormone signaling.

TL;DR: The demonstration that the bHLH-PAS protein Met is an intracellular receptor for JH is a breakthrough and the action of this JH-activated pathway in maintaining the juvenile status is dispensable during early postembryonic development when larvae/nymphs lack competence to metamorphose.
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The MEKRE93 (Methoprene tolerant-Krüppel homolog 1-E93) pathway in the regulation of insect metamorphosis, and the homology of the pupal stage.

TL;DR: It is shown here that Krüppel homolog 1 (Kr-h1), a transducer of the antimetamorphic action of juvenile hormone (JH), represses E93 expression, which appears to be central to the status quo action of JH, which switch adult morphogenesis off and on in species ranging from cockroaches to flies.