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Xiao Liang
Researcher at Xi'an Jiaotong University
Publications - 34
Citations - 370
Xiao Liang is an academic researcher from Xi'an Jiaotong University. The author has contributed to research in topics: Candidate gene & Genome-wide association study. The author has an hindex of 8, co-authored 34 publications receiving 214 citations. Previous affiliations of Xiao Liang include National Health and Family Planning Commission.
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Journal ArticleDOI
Identifying psychiatric disorder-associated gut microbiota using microbiota-related gene set enrichment analysis
Shiqiang Cheng,Bei Han,Miao Ding,Yan Wen,Mei Ma,Lu Zhang,Xin Qi,Bolun Cheng,Ping Li,Om Prakash Kafle,Xiao Liang,Li Liu,Yanan Du,Yan Zhao,Feng Zhang +14 more
TL;DR: The classic gene set enrichment analysis (GSEA) approach was extended to detect the association between gut microbiota and complex diseases using published genome-wide association study (GWAS) and GWAS of gut microbiota summary data and identified several significant associations between psychiatric disorders and gut microbiota.
Journal ArticleDOI
A Genome-wide Expression Association Analysis Identifies Genes and Pathways Associated with Amyotrophic Lateral Sclerosis.
Yanan Du,Yan Wen,Xiong Guo,Jingcan Hao,Wenyu Wang,Awen He,Qianrui Fan,Ping Li,Li Liu,Xiao Liang,Feng Zhang +10 more
TL;DR: This study conducted a genome-wide expression association analysis by summary data-based Mendelian randomization (SMR) method and identified one significant and four suggestive genes associated with ALS, providing novel clues for the genetic mechanism studies of ALS.
Journal ArticleDOI
A large-scale integrative analysis of GWAS and common meQTLs across whole life course identifies genes, pathways and tissue/cell types for three major psychiatric disorders.
Yan Zhao,Xiao Liang,Feng Zhu,Yan Wen,Jiawen Xu,Jian Yang,Miao Ding,Bolun Cheng,Mei Ma,Lu Zhang,Shiqiang Cheng,Cuiyan Wu,Sen Wang,Xi Wang,Yujie Ning,Xiong Guo,Feng Zhang +16 more
TL;DR: A large‐scale integrative analysis of genome‐wide association studies (GWAS) and life course consistent methylation quantitative trait loci (meQTLs) datasets provides novel clues for understanding the genetic mechanism of ADHD, BP and SCZ.
Journal ArticleDOI
Integrating genome-wide association study and expression quantitative trait locus study identifies multiple genes and gene sets associated with schizophrenia.
Yan Zhao,Awen He,Feng Zhu,Miao Ding,Jingcan Hao,Qianrui Fan,Ping Li,Li Liu,Yanan Du,Xiao Liang,Xiong Guo,Feng Zhang,Xiancang Ma +12 more
TL;DR: A large scale integrative analysis of genome‐wide association study (GWAS) and expression quantitative trait loci (eQTLs) data for schizophrenia identified 49 significant genes, whose expression levels were related to schizophrenia.
Journal ArticleDOI
Assessing the Associations of Blood Metabolites With Osteoporosis: A Mendelian Randomization Study.
Li Liu,Yan Wen,Lei Zhang,Peng Xu,Xiao Liang,Yanan Du,Ping Li,Awen He,Qianrui Fan,Jingcan Hao,Wenyu Wang,Xiong Guo,Hui Shen,Qing Tian,Feng Zhang,Hong-Wen Deng +15 more
TL;DR: The results suggest a modest effect of blood metabolites on the variations of BMD and identified several candidate blood metabolites for osteoporosis.