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Awen He
Researcher at National Health and Family Planning Commission
Publications - 25
Citations - 285
Awen He is an academic researcher from National Health and Family Planning Commission. The author has contributed to research in topics: Genome-wide association study & Expression quantitative trait loci. The author has an hindex of 10, co-authored 23 publications receiving 206 citations. Previous affiliations of Awen He include Xi'an Jiaotong University.
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Journal ArticleDOI
A Genome-wide Expression Association Analysis Identifies Genes and Pathways Associated with Amyotrophic Lateral Sclerosis.
Yanan Du,Yan Wen,Xiong Guo,Jingcan Hao,Wenyu Wang,Awen He,Qianrui Fan,Ping Li,Li Liu,Xiao Liang,Feng Zhang +10 more
TL;DR: This study conducted a genome-wide expression association analysis by summary data-based Mendelian randomization (SMR) method and identified one significant and four suggestive genes associated with ALS, providing novel clues for the genetic mechanism studies of ALS.
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Genome-wide DNA methylation profile analysis identifies differentially methylated loci associated with ankylosis spondylitis.
TL;DR: The results demonstrated the altered DNA methylation profile of AS and implicated HLA-DQB1 in the development of AS.
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Comparative analysis of gene expression profiles of hip articular cartilage between non-traumatic necrosis and osteoarthritis.
Wenyu Wang,Yang Liu,Jingcan Hao,Shuyu Zheng,Yan Wen,Xiao Xiao,Awen He,Qianrui Fan,Feng Zhang,Ruiyu Liu +9 more
TL;DR: A systematically comparative study of gene expression profiles between NOFH and osteoarthritis (OA) identified a set of differently expressed genes, GO and pathways for NOFH articular destruction, some of which were also involved in the hip OA.
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Integrating genome-wide association study and expression quantitative trait locus study identifies multiple genes and gene sets associated with schizophrenia.
Yan Zhao,Awen He,Feng Zhu,Miao Ding,Jingcan Hao,Qianrui Fan,Ping Li,Li Liu,Yanan Du,Xiao Liang,Xiong Guo,Feng Zhang,Xiancang Ma +12 more
TL;DR: A large scale integrative analysis of genome‐wide association study (GWAS) and expression quantitative trait loci (eQTLs) data for schizophrenia identified 49 significant genes, whose expression levels were related to schizophrenia.
Journal ArticleDOI
Assessing the Associations of Blood Metabolites With Osteoporosis: A Mendelian Randomization Study.
Li Liu,Yan Wen,Lei Zhang,Peng Xu,Xiao Liang,Yanan Du,Ping Li,Awen He,Qianrui Fan,Jingcan Hao,Wenyu Wang,Xiong Guo,Hui Shen,Qing Tian,Feng Zhang,Hong-Wen Deng +15 more
TL;DR: The results suggest a modest effect of blood metabolites on the variations of BMD and identified several candidate blood metabolites for osteoporosis.