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Xiao Ou Mao
Researcher at Buck Institute for Research on Aging
Publications - 70
Citations - 13692
Xiao Ou Mao is an academic researcher from Buck Institute for Research on Aging. The author has contributed to research in topics: Neurogenesis & Subventricular zone. The author has an hindex of 50, co-authored 70 publications receiving 13133 citations.
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Vascular endothelial growth factor (VEGF) stimulates neurogenesis in vitro and in vivo
TL;DR: Findings implicate the angiogenesis factor VEGF in neurogenesis as well in murine cerebral cortical cultures and in adult rat brain in vivo.
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VEGF-induced neuroprotection, neurogenesis, and angiogenesis after focal cerebral ischemia
TL;DR: In the ischemic brain VEGF exerts an acute neuroprotective effect, as well as longer latency effects on survival of new neurons and on angiogenesis, and that these effects appear to operate independently.
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Neurogenesis in dentate subgranular zone and rostral subventricular zone after focal cerebral ischemia in the rat
Kunlin Jin,Manabu Minami,Jing Q. Lan,Xiao Ou Mao,Sophie Batteur,Roger P. Simon,David A. Greenberg +6 more
TL;DR: A role for ischemia-induced neurogenesis in what may be adaptive processes that contribute to recovery after stroke is supported.
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Increased hippocampal neurogenesis in Alzheimer's disease
Kunlin Jin,Alyson Peel,Xiao Ou Mao,Lin Xie,Barbara A. Cottrell,David C. Henshall,David A. Greenberg +6 more
TL;DR: It is suggested that neurogenesis is increased in AD hippocampus, where it may give rise to cells that replace neurons lost in the disease, and that stimulating hippocampal neuroGenesis might provide a new treatment strategy.
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Vascular endothelial growth factor: Direct neuroprotective effect in in vitro ischemia
TL;DR: In HN33, an immortalized hippocampal neuronal cell line, VEGF reduced cell death associated with an in vitro model of cerebral ischemia: at a maximally effective concentration of 50 ng/ml, V EGF approximately doubled the number of cells surviving after 24 h of hypoxia and glucose deprivation.