Xiaohui Xie

TL;DR: The results suggest that lncRNAs have regulatory roles during early embryonic development, and a subset of them displays highly correlative temporal expression profiles with respect to those of the neighboring genes.

TL;DR: A novel probabilistic mixture model, MixClone, is described for inferring the cellular prevalences of subclonal populations directly from whole genome sequencing of paired normal-tumor samples and it is shown that integrating sequence information from both somatic copy number alterations and allele frequencies can significantly improve the accuracy of inferring tumor subClonal populations.

TL;DR: A model which accurately predicted COVID-19 critical disease risk using comorbidities and presenting vital signs and laboratory values is presented, on derivation and validation cohorts from two different institutions.

TL;DR: Li et al. as mentioned in this paper proposed an end-to-end network for mammographic mass segmentation which employs a fully convolutional network (FCN) to model a potential function, followed by a CRF to perform structured learning.

TL;DR: In this article, an integrated approach, called sparse gradient learning (SGL), is proposed for variable selection and dimension reduction via learning the gradients of the prediction function directly from samples.