Xiaolin Ma

TL;DR: The results first reveal the presynaptic mGluR5-PIP2 pathway whereby oligomeric Aβ induces early synaptic deficits in AD and rescues synaptic and spatial learning and memory deficits in APP/PS1 mice.

TL;DR: It is reported that neuropathic pain-like hypersensitivity induced by common peroneal nerve (CPN) ligation increases nociceptive stimulation-induced responses in glutamatergic LPBN neurons, indicating that a delicate balance between excitatory and inhibitory LPBN neuronal activity governs the development and maintenance of neuropathicPain.

TL;DR: This work reveals that activation of the aPVT-NAc pathway in mice generates a motivation to consume food in a novel environment.

TL;DR: In this article, the authors show that increasing hippocampal astrogenesis during development induces autistic-like behavior in mice and a concurrent decreased E/I ratio in the hippocampus that results from enhanced GABAergic transmission in CA1 pyramidal neurons.

TL;DR: This article showed that early life bilateral whisker trimming (BWT) subsequently affects social discrimination in adult male mice and enhanced activation of the hippocampal dorsal CA3 (dCA3) in BWT mice was observed during social preference tests.