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Xiaoyu Chen
Researcher at Binzhou University
Publications - 30
Citations - 547
Xiaoyu Chen is an academic researcher from Binzhou University. The author has contributed to research in topics: Apoptosis & Cell cycle. The author has an hindex of 13, co-authored 27 publications receiving 356 citations. Previous affiliations of Xiaoyu Chen include Northwest A&F University & Shihezi University.
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Journal ArticleDOI
Cannabidiol Induces Cell Cycle Arrest and Cell Apoptosis in Human Gastric Cancer SGC-7901 Cells
Xin Zhang,Yao Qin,Zhaohai Pan,Minjing Li,Xiaona Liu,Xiaoyu Chen,Guiwu Qu,Ling Zhou,Maolei Xu,Qiusheng Zheng,Defang Li +10 more
TL;DR: Results indicated that CBD could induce G0–G1 phase cell cycle arrest and apoptosis by increasing ROS production, leading to the inhibition of SGC-7901 cell proliferation, thereby suggesting that CBD may have therapeutic effects on gastric cancer.
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Rosmarinic Acid Protects against Inflammation and Cardiomyocyte Apoptosis during Myocardial Ischemia/Reperfusion Injury by Activating Peroxisome Proliferator-Activated Receptor Gamma.
Jichun Han,Jichun Han,Dong Wang,Lei Ye,Peng Li,Wenjin Hao,Xiaoyu Chen,Jun Ma,Bo Wang,Jing Shang,Defang Li,Qiusheng Zheng,Qiusheng Zheng +12 more
TL;DR: The data suggest that RosA attenuates cardiac injury through activating PPARγ and down-regulating NF-κB-mediated signaling pathway, which inhibiting inflammation and cardiomyocyte apoptosis in a rat model of cardiac I/R injury.
Journal ArticleDOI
Cinobufagin Induces Cell Cycle Arrest at the G2/M Phase and Promotes Apoptosis in Malignant Melanoma Cells.
Zhaohai Pan,Xin Zhang,Pengfei Yu,Xiaoyu Chen,Peng Lu,Minjing Li,Xiaona Liu,Li Zhipeng,Fei Wei,Kejun Wang,Qiusheng Zheng,Qiusheng Zheng,Defang Li +12 more
TL;DR: Results indicate that cinobufagin can induce cell cycle arrest at the G2/M phase and apoptosis, leading to inhibition of A375/B16 cell proliferation, and may be useful for melanoma treatment.
Journal ArticleDOI
Isoliquiritigenin-Induced Differentiation in Mouse Melanoma B16F0 Cell Line
Xiaoyu Chen,Bo Zhang,Xuan Yuan,Xuan Yuan,Fan Yang,Jinglei Liu,Hong Zhao,Liangliang Liu,Yanming Wang,Zhenhua Wang,Qiusheng Zheng,Qiusheng Zheng +11 more
TL;DR: It is demonstrated that isoliquiritigenin is a differentiation-inducing agent, and its mechanisms involve ROS accumulation facilitating melanogenesis, which was proven by additional redox modulators.
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Isoliquiritigenin treatment induces apoptosis by increasing intracellular ROS levels in HeLa cells
TL;DR: It is suggested that ISL treatment induced apoptosis by increasing intracellular ROS levels in HeLa cells by inhibiting cell proliferation by inducing apoptosis.