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Xin Wang
Researcher at Peking University
Publications - 1043
Citations - 30114
Xin Wang is an academic researcher from Peking University. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 59, co-authored 762 publications receiving 22731 citations. Previous affiliations of Xin Wang include Beihang University & Sichuan University.
Papers
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Journal ArticleDOI
Calcitonin gene-related peptide inhibits lipopolysaccharide-induced interleukin-12 release from mouse peritoneal macrophages, mediated by the cAMP pathway.
Jun Liu,Mingji Chen,Xin Wang +2 more
TL;DR: The results suggest that LPS‐induced IL‐12 release and gene expression were attenuated by CGRP via an activated cAMP‐protein kinase A (PKA) pathway in mouse peritoneal Mφ.
Journal ArticleDOI
Genetic association of Alzheimer's disease with multiple polymorphisms in alpha-2-macroglobulin
Aleister J. Saunders,Lars Bertram,Kristina Mullin,Andrew J. Sampson,Khushal Latifzai,Sanjay Basu,Jennifer A. Jones,Devon Kinney,Laura MacKenzie-Ingano,Stephen Yu,Marilyn S. Albert,T J Moscarillo,Rodney C.P. Go,Susan Spear Bassett,Mark J. Daly,Nan M. Laird,Xin Wang,Gonul Velicelebi,Steven L. Wagner,David K. Becker,Rudolph E. Tanzi,Deborah Blacker +21 more
TL;DR: Findings continue to support a potential role for A2M or a nearby gene in AD, but the negative case - control studies suggest that any underlying pathogenic polymorphisms have a modest effect, and may operate primarily among individuals with a family history of AD.
Journal ArticleDOI
Advanced Chemical Design for Efficient Lignin Bioconversion
Shangxian Xie,Qining Sun,Yunqiao Pu,Furong Lin,Su Sun,Xin Wang,Arthur J. Ragauskas,Arthur J. Ragauskas,Joshua S. Yuan +8 more
TL;DR: The fundamental mechanisms guided the development of an efficient lignin bioconversion process, where solubilized lign in from laccase–HBT treatment served as a superior substrate for bioconve...
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Unleashing the Power of Bond Cleavage Chemistry in Living Systems
TL;DR: This Outlook summarized the development and applications of bioorthogonal cleavage reactions (BCRs) that restore the functions of chemical structures as well as more complex networks, including the liberation of prodrugs, release of bioconjugates, and in situ reactivation of intracellular proteins.
Journal ArticleDOI
Single-walled carbon nanotube as a unique scaffold for the multivalent display of sugars.
Lingrong Gu,Pengju G. Luo,Haifang Wang,Mohammed J. Meziani,Yi Lin,L. Monica Veca,Li Cao,Fushen Lu,Xin Wang,Robert A. Quinn,Wei Wang,Puyu Zhang,Sebastian Lacher,Ya-Ping Sun +13 more
TL;DR: Through the functionalization, the nanotube apparently serves as a unique scaffold for displaying multiple copies of the sugar molecules in pairs or quartets.