X
Xu Rui Shen
Researcher at Chinese Academy of Sciences
Publications - 9
Citations - 19419
Xu Rui Shen is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Coronavirus & Pneumonia. The author has an hindex of 8, co-authored 9 publications receiving 13853 citations.
Papers
More filters
Journal ArticleDOI
A pneumonia outbreak associated with a new coronavirus of probable bat origin
Peng Zhou,Xing-Lou Yang,Xian Guang Wang,Ben Hu,Lei Zhang,Wei Zhang,Hao Rui Si,Yan Zhu,Bei Li,Chao Lin Huang,Hui-Dong Chen,Jing Chen,Yun Luo,Hua Guo,Ren Di Jiang,Meiqin Liu,Ying Chen,Xu Rui Shen,Xi Wang,Xiao Shuang Zheng,Kai Zhao,Quanjiao Chen,Fei Deng,Lin Lin Liu,Bing Yan,Fa Xian Zhan,Yan-Yi Wang,Gengfu Xiao,Zhengli Shi +28 more
TL;DR: Identification and characterization of a new coronavirus (2019-nCoV), which caused an epidemic of acute respiratory syndrome in humans in Wuhan, China, and it is shown that this virus belongs to the species of SARSr-CoV, indicates that the virus is related to a bat coronav virus.
Journal ArticleDOI
Discovery of a rich gene pool of bat SARS-related coronaviruses provides new insights into the origin of SARS coronavirus
Ben Hu,Leiping Zeng,Xing-Lou Yang,Xing-Yi Ge,Wei Zhang,Bei Li,Jia Zheng Xie,Xu Rui Shen,Yun Zhi Zhang,Ning Wang,Dong Sheng Luo,Xiao Shuang Zheng,Mei Niang Wang,Peter Daszak,Lin-Fa Wang,Jie Cui,Zhengli Shi +16 more
TL;DR: It is hypothesized that the direct progenitor of SARS-CoV may have originated after sequential recombination events between the precursors of these SARSr-CoVs, and highlights the necessity of preparedness for future emergence of Sars-like diseases.
Posted ContentDOI
Discovery of a novel coronavirus associated with the recent pneumonia outbreak in humans and its potential bat origin
Peng Zhou,Xing-Lou Yang,Xian Guang Wang,Ben Hu,Lei Zhang,Wei Zhang,Hao Rui Si,Yan Zhu,Bei Li,Chao Lin Huang,Hui-Dong Chen,Jing Chen,Yun Luo,Hua Guo,Ren Di Jiang,Meiqin Liu,Ying Chen,Xu Rui Shen,Xi Wang,Xiao Shuang Zheng,Kai Zhao,Quanjiao Chen,Fei Deng,Lin Lin Liu,Bing Yan,Fa Xian Zhan,Yan-Yi Wang,Gengfu Xiao,Zhengli Shi +28 more
TL;DR: The identification and characterization of a novel coronavirus (nCoV-2019) which caused an epidemic of acute respiratory syndrome in humans, in Wuhan, China, and it is confirmed that this novel CoV uses the same cell entry receptor, ACE2, as SARS-CoV.
Journal ArticleDOI
Addendum: A pneumonia outbreak associated with a new coronavirus of probable bat origin.
Peng Zhou,Xing-Lou Yang,Xian Guang Wang,Ben Hu,Lei Zhang,Wei Zhang,Hao Rui Si,Yan Zhu,Bei Li,Chao Lin Huang,Hui Dong Chen,Jing Chen,Yun Luo,Hua Guo,Ren Di Jiang,Mei Qin Liu,Ying Chen,Xu Rui Shen,Xi Wang,Xiao Shuang Zheng,Kai Zhao,Quanjiao Chen,Fei Deng,Lin Lin Liu,Bing Yan,Fa Xian Zhan,Yan-Yi Wang,Gengfu Xiao,Zhengli Shi +28 more
Journal ArticleDOI
Pathogenesis of SARS-CoV-2 in Transgenic Mice Expressing Human Angiotensin-Converting Enzyme 2.
Ren Di Jiang,Mei Qin Liu,Ying Chen,Chao Shan,Yi Wu Zhou,Xu Rui Shen,Li Qian,Lei Zhang,Yan Zhu,Hao Rui Si,Qi Wang,Juan Min,Xi Wang,Wei Zhang,Bei Li,Hua Jun Zhang,Ralph S. Baric,Peng Zhou,Xing-Lou Yang,Zhengli Shi +19 more
TL;DR: It is shown that pre-exposure to SARS-CoV-2 could protect mice from severe pneumonia and the hACE2 mouse would be a valuable tool for testing potential vaccines and therapeutics.