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Xuan Wu
Researcher at Peking University
Publications - 8
Citations - 790
Xuan Wu is an academic researcher from Peking University. The author has contributed to research in topics: Chemistry & Nasopharyngeal carcinoma. The author has an hindex of 5, co-authored 6 publications receiving 676 citations. Previous affiliations of Xuan Wu include Sun Yat-sen University.
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Journal ArticleDOI
Whole-genome sequence of Schistosoma haematobium
Neil D. Young,Aaron R. Jex,Bo Li,Shiping Liu,Linfeng Yang,Zijun Xiong,Yingrui Li,Cinzia Cantacessi,Ross S. Hall,Xun Xu,Fangyuan Chen,Xuan Wu,Adhemar Zerlotini,Guilherme Oliveira,Andreas Hofmann,Andreas Hofmann,Guojie Zhang,Xiaodong Fang,Yi Kang,Bronwyn E. Campbell,Alex Loukas,Shoba Ranganathan,Shoba Ranganathan,David Rollinson,Gabriel Rinaldi,Gabriel Rinaldi,Paul J. Brindley,Huanming Yang,Jun Wang,Jian Wang,Robin B. Gasser +30 more
TL;DR: The 385-Mb genome of S. haematobium is sequenced using Illumina-based technology at 74-fold coverage and compared it to sequences from related parasites to provide an unprecedented resource for many fundamental research areas and shows great promise for the design of new disease interventions.
Journal ArticleDOI
Ascaris suum draft genome
Aaron R. Jex,Shiping Liu,Bo Li,Neil D. Young,Ross S. Hall,Yingrui Li,Linfeng Yang,Na Zeng,Xun Xu,Zijun Xiong,Fangyuan Chen,Xuan Wu,Guojie Zhang,Xiaodong Fang,Yi Kang,Garry A. Anderson,Todd W. Harris,Bronwyn E. Campbell,Johnny Vlaminck,Tao Wang,Cinzia Cantacessi,Erich M. Schwarz,Shoba Ranganathan,Peter Geldhof,Peter Nejsum,Paul W. Sternberg,Huanming Yang,Jun Wang,Jing Wang,Robin B. Gasser +29 more
TL;DR: This genome provides a comprehensive resource to the scientific community and underpins the development of new and urgently needed interventions (drugs, vaccines and diagnostic tests) against ascariasis and other nematodiases.
Journal ArticleDOI
The genomic landscape of Epstein-Barr virus-associated pulmonary lymphoepithelioma-like carcinoma
Shaodong Hong,Dongbing Liu,S.F. Luo,Wenfeng Fang,Jianhua Zhan,Sha Fu,Yaxiong Zhang,Xuan Wu,Xuan Wu,Huaqiang Zhou,Xi Chen,Gang Chen,Zhonghan Zhang,Qiufan Zheng,Xiaobo Li,Jinghao Chen,Xingmin Liu,Mengyue Lei,Chen Ye,Jian Wang,Huanming Yang,Xun Xu,Shida Zhu,Yunpeng Yang,Yuanyuan Zhao,Ningning Zhou,Hongyun Zhao,Yan Huang,Lanjun Zhang,Kui Wu,Li Zhang +30 more
TL;DR: A mutational landscape for pulmonary LELC is provided, showing a low burden of somatic mutations and high prevalence of copy number variations, and a road map to facilitate genome-guided personalized treatment is provided.
Journal ArticleDOI
Gemcitabine Plus Cisplatin Versus Fluorouracil Plus Cisplatin as First-Line Therapy for Recurrent or Metastatic Nasopharyngeal Carcinoma: Final Overall Survival Analysis of GEM20110714 Phase III Study
Shaodong Hong,Yaxiong Zhang,Gengsheng Yu,Peijian Peng,Jiewen Peng,Jun Jia,Xuan Wu,Yan Huang,Yunpeng Yang,Qing Lin,Xuping Xi,Mingjun Xu,Dongping Chen,Xiaojun Lu,Rensheng Wang,Xiaolong Cao,Xiaozhong Chen,Zhixiong Lin,Jianping Xiong,Qin Lin,Conghua Xie,Zhihua Li,Jianji Pan,Jin-Gao Li,Shixiu Wu,Yingni Lian,Quanlie Yang,Chong Zhao,Wenfeng Fang,Li Zhang +29 more
TL;DR: The first randomized, phase III study of systemic chemotherapy in recurrent or metastatic nasopharyngeal carcinoma (NPC) was reported in this article, where the authors showed that systemic chemotherapy improved the survival of NPC patients.
Journal ArticleDOI
Osteopontin is a useful predictor of bone metastasis and survival in patients with locally advanced nasopharyngeal carcinoma
Xue Hou,Xuan Wu,Pei Yu Huang,Jianhua Zhan,Ting Zhou,Yuxiang Ma,Tao Qin,Rongzhen Luo,Yanfen Feng,Ying Xu,Likun Chen,Li Zhang +11 more
TL;DR: The findings indicate that OPN is a prognostic biomarker for BM and survival in patients with locally advanced NPC, and therefore it is useful in identifying the patients with an increased risk of cancer progression and BM to guide tailored therapy.