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Xuekui Yu
Researcher at University of California, Los Angeles
Publications - 28
Citations - 1846
Xuekui Yu is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Capsid & Herpes simplex virus. The author has an hindex of 21, co-authored 28 publications receiving 1632 citations. Previous affiliations of Xuekui Yu include University of California, Berkeley & Sun Yat-sen University.
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Journal ArticleDOI
Cryo-EM structure of the mature dengue virus at 3.5-A resolution.
Xiaokang Zhang,Peng Ge,Peng Ge,Peng Ge,Xuekui Yu,Xuekui Yu,Xuekui Yu,Jennifer M Brannan,Jennifer M Brannan,Guo-Qiang Bi,Qinfen Zhang,Stan Schein,Stan Schein,Z. Hong Zhou +13 more
TL;DR: The atomic model of the whole virion from cryo–electron microscopy at 3.5-Å resolution reveals that in the mature virus at neutral extracellular pH, the N-terminal 20-amino-acid segment of M prevents spring-loaded E fusion protein from prematurely exposing its fusion peptide.
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3.88 Å structure of cytoplasmic polyhedrosis virus by cryo-electron microscopy
TL;DR: The polyhedrin-binding domain, a structure that has potential in nanobiotechnology applications, is identified and observed a helix-to-β-hairpin conformational change between the two conformational states of the capsid shell protein in the region directly interacting with genomic RNA.
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Atomic structures of a bactericidal contractile nanotube in its pre- and postcontraction states
TL;DR: It is proposed that the contraction process draws energy from electrostatic and shape complementarities to insert the inner tube through bacterial cell membranes to eventually kill the bacteria.
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In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus
TL;DR: These findings establish the link between sensing of environmental cues by the external proteins and activation of endogenous RNA transcription by the TEC inside the virus.
Journal ArticleDOI
Atomic structure of the human cytomegalovirus capsid with its securing tegument layer of pp150.
TL;DR: This work derived an atomic structure for the herpesvirus-conserved capsid proteins MCP, Tri1, Tri2, and SCP and the HCMV-specific tegument protein pp150, totaling ~4000 molecules and 62 different conformers.