Yan Liu

TL;DR: Five experimental strategies developed by different research groups for extending the longevity of resin-dentin bonds are examined, finding a combination of several of these strategies should result in overcoming the critical barriers to progress currently encountered in dentin bonding.

TL;DR: This critical review provides a broad overview of the current mechanisms involved in bone biomineralization, and the relationship between bone hierarchical structures and the deformation mechanism.

TL;DR: In emulating natural design, the hierarchical nanointerface possesses the capacity to recruit host MSCs and promote endogenous bone regeneration by immunomodulation of macrophage polarization through IL-4.

TL;DR: The ability of using simple non-protein molecules to recapitulate different levels of structural hierarchy in mineralised collagen signifies the ultimate simplicity in Nature's biomineralisation design principles and challenges the need for using more complex recombinant matrix proteins in bioengineering applications.

TL;DR: It is demonstrated that the use of two phosphate-based templating analogs of matrix proteins in the presence of a polycarboxylic acid sequestration analog of ACPs results in a highly ordered intrafibrillar nanoapatite assembly that recapitulates the gap and overlap arrangement of collagen molecules within a collagen fibril.