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Yan Wang
Researcher at The Chinese University of Hong Kong
Publications - 126
Citations - 3452
Yan Wang is an academic researcher from The Chinese University of Hong Kong. The author has contributed to research in topics: Medicine & Catalysis. The author has an hindex of 28, co-authored 115 publications receiving 2762 citations. Previous affiliations of Yan Wang include University of Minnesota & Dalian Institute of Chemical Physics.
Papers
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Journal ArticleDOI
The lncRNA H19 promotes epithelial to mesenchymal transition by functioning as miRNA sponges in colorectal cancer
Wei-Cheng Liang,Weiming Fu,Cheuk Wa Wong,Yan Wang,Wei Mao Wang,Guo Xin Hu,Li Zhang,Li Jia Xiao,David Chi Cheong Wan,Jinfang Zhang,Mary M.Y. Waye +10 more
TL;DR: It is implied that the lncRNA H19 modulated the expression of multiple genes involved in EMT by acting as a competing endogenous RNA, which may build up the missing link between the regulatory miRNA network and EMT progression.
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Papain-directed synthesis of luminescent gold nanoclusters and the sensitive detection of Cu2+.
TL;DR: Highly fluorescent papain stabilized gold nanoclusters (NCs) have been synthesized through a simple wet chemical route and the sensing strategy is also highly selective against the various potential interference ions.
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Cysteine-directed fluorescent gold nanoclusters for the sensing of pyrophosphate and alkaline phosphatase
Yang Chen,Yang Chen,Wenying Li,Yan Wang,Yang Xudong,Jian Chen,Yingnan Jiang,Cong Yu,Quan Lin +8 more
TL;DR: The strategy employed here offers a new way to construct novel nanomaterial-based biosensors that could be useful as label-free fluorescent sensors for the detection of the biologically important molecules pyrophosphate (PPi) and alkaline phosphatase (ALP).
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Downregulation of CFTR promotes epithelial-to-mesenchymal transition and is associated with poor prognosis of breast cancer.
Jie Ting Zhang,Xiaohua Jiang,Xiaohua Jiang,Chen Xie,Hong Cheng,Jian Da Dong,Yan Wang,Kin Lam Fok,Xiao Hu Zhang,Ting Ting Sun,Lai Ling Tsang,Hao Chen,Hao Chen,Xiao Juan Sun,Yiu Wa Chung,Zhi Ming Cai,Wen Guo Jiang,Hsiao Chang Chan,Hsiao Chang Chan +18 more
TL;DR: It is reported that interfering with CFTR function either by its specific inhibitor or lentiviral miRNA-mediated knockdown mimics TGF-β1-induced EMT and enhances cell migration and invasion in MCF-7.
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Diastereo- and enantioselective [3 + 2] cycloaddition reaction of Morita-Baylis-Hillman carbonates of isatins with N-phenylmaleimide catalyzed by Me-DuPhos.
TL;DR: A Me-DuPhos-catalyzed efficient asymmetric [3 + 2] cycloaddition reaction between Morita-Baylis-Hillman carbonates of isatins and N-phenylmaleimide has been developed to afford spirocyclopentaneoxindoles in good yields with excellent diastereo- and enantioselectivies.