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Yanru An

Researcher at Hong Kong University of Science and Technology

Publications -  13
Citations -  162

Yanru An is an academic researcher from Hong Kong University of Science and Technology. The author has contributed to research in topics: Biology & Transcriptome. The author has an hindex of 2, co-authored 5 publications receiving 94 citations.

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β-Spectrin regulates the hippo signaling pathway and modulates the basal actin network.

TL;DR: The abnormal stress fiber-like actin structure on the basal side of follicle cells provides a likely link between the β-spectrin mutations and the loss of the Hippo signaling activity phenotype.
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Apical constriction is driven by a pulsatile apical myosin network in delaminating Drosophila neuroblasts.

TL;DR: It is demonstrated that a contractile actomyosin network across the apical cell surface is organized to drive apical constriction in delaminating neuroblasts, a conserved morphogenetic process important for the generation of cell diversity and maintenance of tissue homeostasis.
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High-resolution 3D spatiotemporal transcriptomic maps of developing Drosophila embryos and larvae.

TL;DR: In this paper , spatial enhanced resolution omics-sequencing (Stereo-seq) was used to dissected the spatiotemporal transcriptomic changes of developing Drosophila with high resolution and sensitivity.
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Single-cell transcriptional profiling reveals cellular and molecular divergence in human maternal–fetal interface

TL;DR: In this article , the authors surveyed the single-cell transcriptomic landscape of human full-term placenta and revealed the heterogeneity of cytotrophoblast cell (CTB) and stromal cell (STR) with the fetal/maternal origin consecutively localized from fetal section (FS), middle section (Mid_S), to maternal section (Mat_S) of maternal-fetal interface.
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Integrative Single-Cell RNA-Seq and ATAC-Seq Analysis of Mesenchymal Stem/Stromal Cells Derived from Human Placenta

TL;DR: This study first provides a comprehensive and integrative view of the transcriptomic and epigenomic features of PMSCs, which paves the way for a deeper understanding of cellular heterogeneity and offers fundamental biological insight of PM SCs subset-based cell therapy.