Y
Yanru An
Researcher at Hong Kong University of Science and Technology
Publications - 13
Citations - 162
Yanru An is an academic researcher from Hong Kong University of Science and Technology. The author has contributed to research in topics: Biology & Transcriptome. The author has an hindex of 2, co-authored 5 publications receiving 94 citations.
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Journal ArticleDOI
β-Spectrin regulates the hippo signaling pathway and modulates the basal actin network.
TL;DR: The abnormal stress fiber-like actin structure on the basal side of follicle cells provides a likely link between the β-spectrin mutations and the loss of the Hippo signaling activity phenotype.
Journal ArticleDOI
Apical constriction is driven by a pulsatile apical myosin network in delaminating Drosophila neuroblasts.
Yanru An,Guosheng Xue,Yang Shaobo,Deng Mingxi,Xiaowei Zhou,Weichuan Yu,Toyotaka Ishibashi,Lei Zhang,Yan Yan +8 more
TL;DR: It is demonstrated that a contractile actomyosin network across the apical cell surface is organized to drive apical constriction in delaminating neuroblasts, a conserved morphogenetic process important for the generation of cell diversity and maintenance of tissue homeostasis.
Journal ArticleDOI
High-resolution 3D spatiotemporal transcriptomic maps of developing Drosophila embryos and larvae.
Mingyue Wang,Qinan Hu,Tian-Jing Lv,Yuhang Wang,Qing Lan,Rong Xiang,Zhencheng Tu,Ya-rong Wei,Kai Han,Chang Shi,Junfu Guo,Chao Liu,Tao Yang,Wen Fei Du,Yanru An,Mengnan Cheng,Jiangshan Xu,Hao Rong Lu,Wangsheng Li,Shaofang Zhang,Ao Chen,Wei Chen,Yuxiang Li,Xiaoshan Shayna Wang,XunHua Xu,Yuhui Hu,Long Liu +26 more
TL;DR: In this paper , spatial enhanced resolution omics-sequencing (Stereo-seq) was used to dissected the spatiotemporal transcriptomic changes of developing Drosophila with high resolution and sensitivity.
Journal ArticleDOI
Single-cell transcriptional profiling reveals cellular and molecular divergence in human maternal–fetal interface
Quanlei Wang,Jinlu Li,Shengpeng Wang,Qiuting Deng,Yanru An,Yanan Xing,Xi Dai,Zelong Li,Qiwang Ma,Kuixing Wang,Chuanyu Liu,Yue Yuan,Guoyi Dong,Tao Zhang,Huanming Yang,Yutao Du,Yong Hou,Weilin Ke,Zhouchun Shang +18 more
TL;DR: In this article , the authors surveyed the single-cell transcriptomic landscape of human full-term placenta and revealed the heterogeneity of cytotrophoblast cell (CTB) and stromal cell (STR) with the fetal/maternal origin consecutively localized from fetal section (FS), middle section (Mid_S), to maternal section (Mat_S) of maternal-fetal interface.
Journal ArticleDOI
Integrative Single-Cell RNA-Seq and ATAC-Seq Analysis of Mesenchymal Stem/Stromal Cells Derived from Human Placenta
Jinlu Li,Quanlei Wang,Yanru An,Xiaoyan Chen,Yanan Xing,Qiuting Deng,Zelong Li,Shengpeng Wang,Xi Dai,Ning Liang,Yong Hou,Huanming Yang,Zhouchun Shang +12 more
TL;DR: This study first provides a comprehensive and integrative view of the transcriptomic and epigenomic features of PMSCs, which paves the way for a deeper understanding of cellular heterogeneity and offers fundamental biological insight of PM SCs subset-based cell therapy.