Y
Yao Zhang
Researcher at Sun Yat-sen University
Publications - 8
Citations - 158
Yao Zhang is an academic researcher from Sun Yat-sen University. The author has contributed to research in topics: Human proteome project & NeXtProt. The author has an hindex of 7, co-authored 8 publications receiving 110 citations. Previous affiliations of Yao Zhang include Chinese Academy of Sciences & Protein Sciences.
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Journal ArticleDOI
Quantitative Proteomics Reveals Membrane Protein-Mediated Hypersaline Sensitivity and Adaptation in Halophilic Nocardiopsis xinjiangensis.
Yao Zhang,Yao Zhang,Yanchang Li,Yongguang Zhang,Zhi Qiang Wang,Zhi Qiang Wang,Mingzhi Zhao,Na Su,Tao Zhang,Lingsheng Chen,Lingsheng Chen,Wei Wei,Jing Luo,Jing Luo,Yanxia Zhou,Yanxia Zhou,Yongru Xu,Yongru Xu,Ping Xu,Ping Xu,Ping Xu,Wen-Jun Li,Wen-Jun Li,Wen-Jun Li,Yong Tao +24 more
TL;DR: Overall, regulation of membrane proteins may provide a major protection strategy against hyperosmotic stress.
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Enrichment-Based Proteogenomics Identifies Microproteins, Missing Proteins, and Novel smORFs in Saccharomyces cerevisiae.
TL;DR: This study demonstrates that there are potential smORF candidates to be annotated in an extensively studied organism but also presents an efficient strategy for the discovery of small MPs.
Journal ArticleDOI
Quantitative proteomics reveals mitochondrial respiratory chain as a dominant target for carbon ion radiation: Delayed reactive oxygen species generation caused DNA damage.
Peng-Cheng Fan,Yao Zhang,Yao Zhang,Yu Wang,Wei Wei,Yan-Xia Zhou,Yi Xie,Xin Wang,Yingzi Qi,Lei Chang,Zheng-Ping Jia,Zhe Zhou,Hua Guan,Hong Zhang,Ping Xu,Ping Xu,Ping-Kun Zhou +16 more
TL;DR: A quantitative proteomic analysis to investigate the mechanism of carbon ion irradiation on human AHH‐1 lymphoblastoid cells provided a novel target for cell self‐repair against heavy ion radiation‐induced cellular damage.
Journal ArticleDOI
Multi-Protease Strategy Identifies Three PE2 Missing Proteins in Human Testis Tissue
TL;DR: It was found that nonconventional proteases could improve the peptide diversity and sequence coverage compared with Trypsin, and three PE2 MPs in neXtProt 2017-01 have been identified, considered as exemplary examples of MPs found by exceptional criteria.
Journal ArticleDOI
Multiproteases Combined with High-pH Reverse-Phase Separation Strategy Verified Fourteen Missing Proteins in Human Testis Tissue
Jinshuai Sun,Jinshuai Sun,Jiahui Shi,Jiahui Shi,Yihao Wang,Yang Chen,Yanchang Li,Degang Kong,Lei Chang,Fengsong Liu,Zhitang Lv,Yue Zhou,Fuchu He,Yao Zhang,Ping Xu,Ping Xu,Ping Xu +16 more
TL;DR: This study verified 14 MPs (PE2) in neXtProt (2018-01) after spectrum quality analysis, isobaric post-translational modification, and single amino acid variant filtering, and synthesized peptide matching, which showed that 3 of 14 MPs were testis-specific proteins.