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Yaqi Zhang
Researcher at Chinese Academy of Sciences
Publications - 5
Citations - 43
Yaqi Zhang is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 1, co-authored 2 publications receiving 7 citations.
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Journal ArticleDOI
Rapid transport of germ-mimetic nanoparticles with dual conformational polyethylene glycol chains in biological tissues.
Yiwei Yang,Falin Tian,Di Nie,Yuan Liu,Kun Qian,Miaorong Yu,Aohua Wang,Yaqi Zhang,Xinghua Shi,Yong Gan +9 more
TL;DR: In vivo results proved the superior tumor permeability and improved oral bioavailability provided by the GMNP (21.9-fold over administration of crystalline drugs) and offer useful guidelines for the rational design of NPs by manipulating surface polymer conformation to realize multiple functions and to enhance delivery efficacy.
Journal ArticleDOI
The upregulated intestinal folate transporters direct the uptake of ligand-modified nanoparticles for enhanced oral insulin delivery
Jingyi Li,Catherine M. Worsley,Jingyi Li,Yaqi Zhang,Miaorong Yu,Aohua Wang,Yu Qiu,Weiwei Fan,Lars Hovgaard,Mingshi Yang,Yiming Li,Rui Wang,Xiuying Li,Yong Gan +13 more
TL;DR: It is demonstrated that the upregulated intestinal transporters could direct the uptake of ligand-modified nanoparticles by mediating the endocytosis and intracellular trafficking of lig and- modified nanoparticles via the transporter-mediated pathway.
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Ligand-modified nanocarriers for oral drug delivery: Challenges, rational design, and applications.
TL;DR: In this paper , the extracellular and cellular barriers to orally administered nanocarriers in the gastrointestinal (GI) tract and new discoveries regarding the GI protein corona and the sequential transport barriers that impede the preplanned movements of LMNCs after oral administration are discussed.
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Physicochemical, structural, and digestive properties of pea starch obtained via ultrasonic-assisted alkali extraction
Ning Wang,Ning Shi,Hong-Lin Fei,Yuan Liu,Yaqi Zhang,Zhijiang Li,Changqing Ruan,Dongjie Zhang +7 more
TL;DR: In this paper , the efficiency of combining ultrasonic with alkali in the extraction of pea starch was evaluated and compared to conventional alkali extraction using single-factor experiments and response surface methodology.
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Shape and Shear Stress Impact on the Toxicity of Mesoporous Silica Nanoparticles: In Vitro and In Vivo Evidence.
Yaxin Cheng,Jinsong Tao,Yaqi Zhang,Long Xi,Run Han,Meng Xu,Simon Ming-Yuen Lee,Wei Ge,Yong Gan,Ying Zheng +9 more
TL;DR: In this paper , the impact of shape and shear stress on the toxicity of mesoporous silica nanoparticles (MSNs) after injection was investigated in human umbilical vein endothelial cells.