Yasuharu Ninomiya

TL;DR: In this paper, double immunostaining of the pituitary for Ad4BP and trophic peptide hor- mones, FSH, TSH, and ACTH, indicated a re-stricted localization of the transcription factor to the gonadotroph.

TL;DR: Dose-response of an induction of a germline mutation was studied at a hypervariable mouse minisatellite locus, Ms6hm, which consists of tandem repeats of a sequence motif GGGCA, and the spermatids stage was most sensitive to radiation and a statistically significant dose-response was observed.

TL;DR: expression of the four ELP isoforms was studied in mouse tissues and in tissue culture cells by quantitative reverse transcriptase-polymerase chain reaction (RT-PCR) analysis and complex patterns of expression of these isoforms were observed in various tissues.

TL;DR: The present study indicates a possible involvement of K-ras mutation and c-myc amplification in induction of genetic instability in methylcholanthrene-induced mouse sarcomas.

TL;DR: Interestingly, the activator-type ELP isoforms were capable of repressing retinoic acid-induced transactivation through binding to the retinoi acid receptor binding element, suggesting that competition for target DNA binding is a general mechanism of transcriptional repression by ELPisoforms.