Y
Yasunori Takayama
Researcher at National Institutes of Natural Sciences, Japan
Publications - 29
Citations - 1129
Yasunori Takayama is an academic researcher from National Institutes of Natural Sciences, Japan. The author has contributed to research in topics: Transient receptor potential channel & TRPV1. The author has an hindex of 14, co-authored 27 publications receiving 772 citations. Previous affiliations of Yasunori Takayama include Showa University & Graduate University for Advanced Studies.
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Journal ArticleDOI
Functional Role for Piezo1 in Stretch-evoked Ca2+ Influx and ATP Release in Urothelial Cell Cultures
Tatsuya Miyamoto,Tsutomu Mochizuki,Hiroshi Nakagomi,Satoru Kira,Masaki Watanabe,Yasunori Takayama,Yoshiro Suzuki,Schuichi Koizumi,Masayuki Takeda,Makoto Tominaga +9 more
TL;DR: Evidence is provided for a critical role for the Piezo1 channel, a newly identified mechanosensory molecule, in the mouse bladder urothelium and results suggest that inhibition ofPiezo1 might provide a promising means of treating bladder dysfunction.
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Pain-enhancing mechanism through interaction between TRPV1 and anoctamin 1 in sensory neurons
TL;DR: It is reported that the capsaicin-evoked action potential could be induced by two components: a cation influx-mediated depolarization caused by TRPV1 activation and a subsequent anion efflux-mediateddepolarization via activation of anoctamin 1 (ANO1), a calcium-activated chloride channel, resulting from the entry of calcium through TRpV1.
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Cell surface flip-flop of phosphatidylserine is critical for PIEZO1-mediated myotube formation
Masaki Tsuchiya,Yuji Hara,Yuji Hara,Masaki Okuda,Karin Itoh,Ryotaro Nishioka,Akifumi Shiomi,Kohjiro Nagao,Masayuki X. Mori,Yasuo Mori,Junichi Ikenouchi,Ryo Suzuki,Motomu Tanaka,Motomu Tanaka,Tomohiko Ohwada,Junken Aoki,Motoi Kanagawa,Tatsushi Toda,Yosuke Nagata,Ryoichi Matsuda,Yasunori Takayama,Makoto Tominaga,Masato Umeda +22 more
TL;DR: It is suggested that cell surface flip-flop of phosphatidylserine acts as a molecular switch for PIEZO1 activation that governs proper morphogenesis during myotube formation.
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Modulation of water efflux through functional interaction between TRPV4 and TMEM16A/anoctamin 1
TL;DR: Physical and functional interactions between TRPV4 and ANO1 can modulate water transport in the choroid plexus through functional interaction between TMEM16A/anoctamin 1.
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Lack of TRPV2 impairs thermogenesis in mouse brown adipose tissue
Wu-Ping Sun,Kunitoshi Uchida,Kunitoshi Uchida,Yoshiro Suzuki,Yoshiro Suzuki,Yiming Zhou,Min-Ji Kim,Yasunori Takayama,Yasunori Takayama,Nobuyuki Takahashi,Tsuyoshi Goto,Shigeo Wakabayashi,Teruo Kawada,Yuko Iwata,Makoto Tominaga,Makoto Tominaga +15 more
TL;DR: It is concluded that TRPV2 has a role in BAT thermogenesis and could be a target for human obesity therapy.