Yasuo Kikuchi

TL;DR: RNA blot analysis showed that mRNAs for BTEB and Sp1 were expressed in all tissues tested, but their concentrations varied independently in tissues, while the former mRNA was rich in the brain, kidney, lung and testis, whereas the latter was relatively abundant in the thymus and spleen.

TL;DR: The Arnt homodimer binds the sequence of adenovirus major late promoter (MLP) with the E box core sequence CACGTG, suggesting that the CAC half of the XRE, CACGCN(A/T), recognized by the AhR-Arnt heterodimer is a target for Arnt.

TL;DR: It is concluded that mSim2 is an ortholog of hSim2, which is proposed to be a candidate gene responsible for Down's syndrome, and whole-mount in situ hybridization showed restricted and characteristic expression patterns of the two mSim mRNAs in various tissues and organs during embryogenesis.

TL;DR: Results demonstrate that a novel induction mechanism is present in which the AhR-Arnt heterodimer functions as a coactivator, and a repeated sequence separated by six nucleotides is important for expression.

TL;DR: The regulatory mechanisms of CYP1A1 gene expression are discussed by summarizing the present state of knowledge about properties of the DNA regulatory elements and their cognate DNA‐binding factors.