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Yehia Daaka
Researcher at University of Florida
Publications - 98
Citations - 11639
Yehia Daaka is an academic researcher from University of Florida. The author has contributed to research in topics: G protein-coupled receptor & Receptor. The author has an hindex of 46, co-authored 94 publications receiving 11222 citations. Previous affiliations of Yehia Daaka include Howard Hughes Medical Institute & Georgia Regents University.
Papers
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Journal ArticleDOI
G proteins in cancer: the prostate cancer paradigm.
TL;DR: An in-depth analysis of the role of heterotrimeric guanine nucleotide-binding proteins (G proteins) in stimulating androgen-independent growth of prostate cancer cells is provided.
Journal Article
Bradykinin receptor subtype 1 expression and function in prostate cancer
TL;DR: Findings identify B1R as an early marker for pathological growth of the prostate and suggest its potential utility as a drug target effective for the treatment of prostate cancer.
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PGE2 promotes angiogenesis through EP4 and PKA Cγ pathway
Yushan Zhang,Yehia Daaka +1 more
TL;DR: Evidence is provided that PGE2 promotes the in vitro tube formation of human microvascular endothelial cells, ex vivo vessel outgrowth of aortic rings, and actual in vivo angiogenesis, and rationale for use of selective EP4 signal inhibitors as a probable strategy to control pathologicAngiogenesis is provided.
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Lysophosphatidic acid-regulated mitogenic ERK signaling in androgen-insensitive prostate cancer PC-3 cells.
Pao F. Kue,Jason S. Taub,Liza Barki Harrington,Roberto D. Polakiewicz,Axel Ullrich,Yehia Daaka +5 more
TL;DR: In this paper, a positive cooperative interaction between the G protein-coupled lysophosphatidic acid (LPA) and tyrosine kinase epidermal growth factor (EGF) receptors in androgen-insensitive prostate cancer PC-3 cells was shown.
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Mitogenic action of LPA in prostate.
TL;DR: Data is presented demonstrating a correlation between the mitogenic effects of LPA and expression of the lp(A1) gene in the prostate cancer cells.