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Yilmaz Alguel
Researcher at Imperial College London
Publications - 19
Citations - 1157
Yilmaz Alguel is an academic researcher from Imperial College London. The author has contributed to research in topics: Membrane protein & Efflux. The author has an hindex of 12, co-authored 19 publications receiving 993 citations. Previous affiliations of Yilmaz Alguel include Rutherford Appleton Laboratory.
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Journal ArticleDOI
Clustering procedures for the optimal selection of data sets from multiple crystals in macromolecular crystallography
James Foadi,Pierre Aller,Yilmaz Alguel,Alexander D. Cameron,Danny Axford,Robin L. Owen,Wes Armour,David G. Waterman,So Iwata,Gwyndaf Evans +9 more
TL;DR: A systematic approach to the scaling and merging of data from multiple crystals in macromolecular crystallography is introduced and explained.
Journal ArticleDOI
Crystal structure of the anion exchanger domain of human erythrocyte band 3
Takatoshi Arakawa,Takami Kobayashi-Yurugi,Yilmaz Alguel,Hiroko Iwanari,Hinako Hatae,Momi Iwata,Yoshito Abe,Tomoya Hino,Chiyo Ikeda-Suno,Hiroyuki Kuma,Dongchon Kang,Takeshi Murata,Takao Hamakubo,Alexander D. Cameron,Takuya Kobayashi,Naotaka Hamasaki,So Iwata +16 more
TL;DR: The crystal structure of the transmembrane anion exchanger domain of AE1 is reported, which includes 14 trans Membrane helices and provides a basis for understanding the effects of mutations that lead to red blood cell diseases and also gives insight into the mechanism of ion transport.
Journal ArticleDOI
Benchmarking Membrane Protein Detergent Stability for Improving Throughput of High-Resolution X-ray Structures
Yo Sonoda,Simon Newstead,Nien-Jen Hu,Yilmaz Alguel,Emmanuel Nji,Konstantinos Beis,Shoko Yashiro,Chiara Lee,James Leung,Alexander D. Cameron,Bernadette Byrne,So Iwata,David A. Drew +12 more
TL;DR: It is suggested that by monitoring membrane protein stability with reference to the benchmarks described here, greater efforts can be placed on constructs and conditions more likely to yield high-resolution structures.
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Band 3, the human red cell chloride/bicarbonate anion exchanger (AE1, SLC4A1), in a structural context.
Reinhart A. F. Reithmeier,Joseph R. Casey,Antreas C. Kalli,Mark S.P. Sansom,Yilmaz Alguel,So Iwata +5 more
TL;DR: The crystal structure of the dimeric membrane domain of human Band 3(1), the red cell chloride/bicarbonate anion exchanger 1 (AE1, SLC4A1), provides a structural context for over four decades of studies into this historic and important membrane glycoprotein.
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Crystal structures of multidrug binding protein TtgR in complex with antibiotics and plant antimicrobials.
Yilmaz Alguel,Cuixiang Meng,Wilson Terán,Tino Krell,Juan L. Ramos,María-Trinidad Gallegos,Xiaodong Zhang +6 more
TL;DR: Five high-resolution crystal structures of TtgR from the solvent-tolerant strain DOT-T1E are reported, including T TGR in complex with common antibiotics and plant secondary metabolites, which provides structural basis for the unique ligand binding properties of TTGR.