Xiaodong Zhang

TL;DR: A general profile for the proteins of the TetR family of repressors is developed, made up of 47 amino acid residues that correspond to the helix-turn-helix DNA binding motif and adjacent regions in the three- dimensional structures of TetR, QacR, CprB, and EthR, four family members for which the function and three-dimensional structure are known.

TL;DR: Two structures are reported: a crystal structure of the N-terminal and D1 ATPase domains of murine p97 and a cryoelectron microscopy structure of full-length rat p97, showing that the D1 and D2 hexamers pack in a tail-to-tail arrangement, and that the N domain is flexible.

TL;DR: The scanning transmission x-ray microscope at the National Synchrotron Light Source has been used to record XANES spectra from 0.01-square-micrometer regions of organic specimens to identify and map separate phases in various polymer blends and to map the DNA distribution in chromosomes.

TL;DR: It is shown that the emerging H7N9 avian influenza virus poses a potentially high risk to humans, and current seasonal vaccination could not provide protection.

TL;DR: The first three‐dimensional structure and fold of a BRCT domain determined by X‐ray crystallography at 3.2 Å resolution is described and the established structure of an XRCC1 BRCT homodimer suggests potential protein–protein interaction sites for the complementaryBRCT domain in DNA ligase III.