Ying Pei

TL;DR: It was suggested that 1,2,4,6‐tetra‐O‐galloyl‐β‐d‐glucose (1246TGG) might exert anti‐HSV activity both by inactivating extracellular viral particles and by inhibiting viral biosynthesis in host cells.

TL;DR: The biphasic F-actin dynamics in HSV-1 neuronal infection is demonstrated for the first time and the association of F-Actin with the changes in the expression and activity of cofilin 1 is confirmed to provide insight into the mechanism by which HSV -1 productively infects neuronal cells and causes pathogenesis.

TL;DR: A quantitative proteomics analysis of autophagy-deficient mouse embryonic fibroblast cells using iTRAQ labeling coupled with on-line 2D LC/MS/MS demonstrated a close relationship between F-actin and autophagic and provide the basis for further investigation of their interactions.

TL;DR: Results suggested that down-regulating cofilin1 plays a role in PGG inhibiting HSV-1 infection, and PGG may be a promising anti-herpesvirus agent for drug development.

TL;DR: Five new 7-O-methylkaempferol and -quercetin glycosides, namely, nervilifordins A-E (1-5), were isolated from the whole plant of Nervilia fordii and their structures were elucidated on the basis of extensive spectroscopic analyses, including HSQC, HMBC, ROESY, and chemical methods.